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The Retroviridae

  • Jay A. Levy

Part of the The Viruses book series (VIRS)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Edward Barker, Susan W. Barnett, Leonidas Stamatatos, Jay A. Levy
    Pages 1-96
  3. S.-H. Ignatius Ou, Richard B. Gaynor
    Pages 97-184
  4. B. Matija Peterlin
    Pages 185-238
  5. Martin Löchelt, Rolf M. Flügel
    Pages 239-292
  6. Suraiya Rasheed
    Pages 293-408
  7. Francisco González-Scarano, Neal Nathanson, Paul K. Y. Wong
    Pages 409-490
  8. Robert F. Garry, Arthur M. Krieg, William P. Cheevers, Ronald C. Montelaro, Hana Golding, Cesar D. Fermin et al.
    Pages 491-603
  9. Ronald C. Montelaro, Dani P. Bolognesi
    Pages 605-656
  10. Back Matter
    Pages 657-670

About this book

Introduction

depth overview of the retrovirus family. I have greatly enjoyed and learned from this experience. Each chapter is an excellent introduction to the topic covered and provides a good foundation for further work in the field. Jay A. Levy University of California School of Medicine San Francisco, California REFERENCES Brown, E. W., Yuhki, N., Packer, C., and O'Brien, S. J., 1994, A lion lentivirus related to feline immunodeficiency virus: Epidemiologic and phylogenetic aspects, ,. Viral. 68:5953-5968. Merza, M., Larsson, E., Steen, M., and Morein, B., 1994, Association of a retrovirus with a wasting condition in the Swedish moose, Virology 202:956-961. Contents Chapter 1 The Human Immunodeficiency Viruses Edward Barker, Susan W Barnett, Leonidas Stamatatos, and Jay A. Levy I. Introduction .................................................... 1 TI. Description of Agent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 A. Virus Structure .............................................. 2 B. Genetic Organization and Gene Function ...................... 2 TIL Transmission.................................................... 7 A. General Observations ........................................ 7 B. HIV Transmission by Blood and Blood Products ................ 8 C. HIV Transmission by Genital Fluids ........................... 10 D. HIV Transmission by Other Body Fluids ....................... 12 E. Mother-to-Child Transmission ................................ 12 IV. HIV Infection of the Cell . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 . . . . . . . . . . . . . A. Introduction ................................................. 13 B. HIV-Cell Interaction............ ............... .............. 15 C. CD4-Induced gp120 Conformational Changes .................. 16 D. Soluble CD4-Induced gp120-gp41 Dissociation..... ............ 16 E. gp120 Proteolytic Cleavage ................................... 17 F. pH-Independent Membrane Fusion ............................ 19 G. Transmission of HIV by Cell-to-Cell Fusion.................... 19 H. Additional Cell Surface Receptors for HIV ..................... 20 I. The Envelope Region and Cell Tropism ........ . . . . . . . . . . . . 21 . . . .

Keywords

biology gene gene expression immunodeficiency molecular biology nervous system retroviruses vaccine virus

Editors and affiliations

  • Jay A. Levy
    • 1
  1. 1.School of MedicineUniversity of CaliforniaSan FranciscoUSA

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