Statistical Methods for Quality of Life Studies

Design, Measurements and Analysis

  • Mounir Mesbah
  • Bernard F. Cole
  • Mei-Ling Ting Lee

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. David R. Cox
      Pages 3-5
  3. Measurement, Scale Development, and Study Design

  4. Analysis and Interpretation of Multiple Endpoints

    1. Front Matter
      Pages 101-101
    2. Pascale Tubert-Bitter, Daniel A. Bloch, Tze L. Lai
      Pages 113-128
  5. Item Response Theory and Rasch Models

    1. Front Matter
      Pages 141-141
    2. Agnes Hamon, Mounir Mesbah
      Pages 155-168
    3. Svend Kreiner, Karl Bang Christensen
      Pages 187-203
  6. Joint Analysis of Quality of Life and Survival

    1. Front Matter
      Pages 205-205
    2. Natacha Heutte, Catherine Huber-Carol
      Pages 207-218
    3. Mei-Ling Ting Lee, G. Alex Whitmore
      Pages 219-230
    4. Lucile Awad, Emmanuel Zuber, Mounir Mesbah
      Pages 231-243
  7. Quality-Adjusted Survival Analysis and Related Methods

  8. Methods for Informatively Missing Longitudinal Quality-of-Life Data

    1. Front Matter
      Pages 301-301
    2. Michel Chavance
      Pages 303-305
    3. Geert Molenberghs, Herbert Thijs, Geert Verbeke, Bart Michiels, Michael G. Kenward
      Pages 339-351
    4. Margaret C. Wu, Craig B. Borkowf, Paul S. Albert
      Pages 353-364

About this book


On October 16 and 17, 2000, we hosted an international workshop entitled "Statistical Design, Measurement, and Analysis of Health Related Quality of Life." The workshop was held in the beautiful city of Arradon, South Brittany, France with the main goal of fostering an interdisciplinary forum for discussion of theoretical and applied statistical issues arising in studies of health-related quality of life (HRQoL). Included were biostatisticians, psychometricians and public health professionals (e.g., physicians, sociologists, psychologists) active in the study ofHRQoL. In assembling this volume, we invited each conference participant to contribute a paper based on his or her presentation and the ensuing and very interesting discussions that took place in Arradon. All papers were peer-reviewed, by anonymous reviewers, and revised before final editing and acceptance. Although this process was quite time­ consuming, we believe that it greatly improved the volume as a whole, making this book a valuable contribution to the field ofHRQoL research. The volume presents a broad spectrum of papers presented at the Workshop, and thus illustrates the range of current research related to the theory, methods and applications of HRQoL, as well as the interdisciplinary nature ofthis work. Following an introduction written by Sir David Cox, it includes 27 articles organized into the following chapters.


Assessment Censoring Item Measure Survival analysis best fit

Editors and affiliations

  • Mounir Mesbah
    • 1
  • Bernard F. Cole
    • 2
  • Mei-Ling Ting Lee
    • 3
  1. 1.Université de Bretagne-SudFrance
  2. 2.Dartmouth CollegeUSA
  3. 3.Harvard UniversityUSA

Bibliographic information