Advances in Myocardiology

1. Oxygen Free Radicals and Myocardial Injury

   1. Oxygen Radicals and Tissue Damage in Heart Hypertrophy

      • Carlo Guarnieri, Claudio Muscari, Claudio M. Caldarera

      Pages 191-199

   2. Disturbances of the Heart Structure and Function in Chronic Hemolytic Anemia, Their Compensation with Increased Coronary Flow, and Their Prevention with Ionol, an Inhibitor of Lipid Peroxidation

      • F. Z. Meerson, M. E. Evsevieva

      Pages 201-211

2. Structural Components of the Myocyte and Its Matrix

   1. Front Matter

      Pages 213-213

      PDF

   2. The Role of Actin-Binding Proteins Vinculin, Filamin, and Fibronectin in Intracellular and Intercellular Linkages in Cardiac Muscle

      • Victor E. Koteliansky, Vladimir P. Shirinsky, Gennady N. Gneushev, Michail A. Chernousov

      Pages 215-221

   3. Intercellular Junctions and the Cardiac Intercalated Disk

      • N. J. Severs

      Pages 223-242

   4. Extracellular Structures in Heart Muscle

      • Thomas F. Robinson, Leona Cohen-Gould, Renee M. Remily, Joseph M. Capasso, Stephen M. Factor

      Pages 243-255

   5. Ventricular Collagen Matrix and Alterations

      • James B. Caulfield, Sun Ben Tao, Maurice Nachtigal

      Pages 257-269

3. Sarcolemmal Sodium Exchange

   1. Front Matter

      Pages 271-271

      PDF

   2. Single Cells and Rapid Inward Sodium Current

      • Trevor Powell

      Pages 273-278

   3. Influence of Na/K Pump Current on Action Potentials in Purkinje Fibers

      • David C. Gadsby

      Pages 279-294

   4. Na-Ca Exchange in Cardiac Tissues

      • D. Ellis

      Pages 295-312

   5. The Effects of Intracellular Na on Contraction and Intracellular pH in Mammalian Cardiac Muscle

      • R. D. Vaughan-Jones, D. A. Eisner, W. J. Lederer

      Pages 313-330

4. Influence of Lipids on Membranes

   1. Front Matter

      Pages 331-331

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   2. Interaction of Amphiphilic Molecules with Biological Membranes

      • L. Herbette, C. A. Napolitano, F. C. Messineo, A. M. Katz

      Pages 333-346

   3. Phospholipid Alterations and Membrane Injury during Myocardial Ischemia

      • Kenneth R. Chien, James T. Willerson, L. Maximilian Buja

      Pages 347-353

5. Back Matter

   Pages 355-368

   PDF

The Eleventh World Congress of the International Society for Heart Re­ search 1983 provided an opportunity to review some of the growing points in our knowledge of the structure and function of the myocardium. Those at the meeting will recall how London suddenly went tropical. Yet aseries of scintillating reviews held over six hundred scientists captive in the lecture halls of Imperial College. There were sessions on nuclear magnetic reso­ nance, the molecular basis of electrophysiology, calmodulin, protein syn­ thesis and degradation, oxygen free radicals, the structural components of the myocyte, sarcolemmal sodium exchange, and the influence of lipids on membranes. Here we have gathered together, as quickly as possible, a number of the presentations of the speakers invited to the symposia. They give, we believe, a striking picture ofthe diversity oftechnology and scientific enquiry which underlies this immensely active domain of modern cardiology. If only our clinical colleagues were more aware of it! Peter Harris Philip A. Poole-Wilson London v Contents Evolution, Cardiac Failure, and Water Metabolism: Presidential Address . . . . . . . . . . . . . . . . . . .

• cardiology
• electrophysiology
• heart
• physiology

• Cardiothoracic Institute, University of London, London, England

  Peter Harris, Philip A. Poole-Wilson

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