The Bile Acids Chemistry, Physiology, and Metabolism

Volume 1: Chemistry

  • Padmanabhan P. Nair
  • David Kritchevsky

Table of contents

  1. Front Matter
    Pages i-xi
  2. David Kritchevsky, Padmanabhan P. Nair
    Pages 1-10
  3. William H. Elliott
    Pages 47-93
  4. S. L. Hsia
    Pages 95-120
  5. J. Sjövall, P. Eneroth, R. Ryhage
    Pages 209-248
  6. Donald M. Small
    Pages 249-356
  7. Back Matter
    Pages 357-372

About this book

Introduction

The bile acids as principal end products of cholesterol metabolism occupy a focal position in our understanding of the role of steroids in bio­ logical systems. The biogenesis of bile acids from cholesterol in higher ani­ mals, and their functions in regulating sterol metabolism and in gastrointestinal physiology have been elucidated by the development of elegant methodo­ logical approaches during the last two decades. The molecular pleomorphism exhibited by the bile acids and bile alcohols in the animal kingdom is a classic example of their role in biochemical evolution. The total story of the bile acids, their chemistry, their role in normal and abnormal physiological processes, and their significance in biochemical evolution has never been available in the form of a comprehensive treatise written in the words of those who have contributed to the development of our knowledge in this area. The Bile Acids, in two volumes, will serve to fill this void, and will also bring together information which will prove in­ valuable to both the biochemist and the medical scientist. We wish to thank Mrs. Sally Wiseman and Mrs. Lillian Haas for their invaluable assistance with the editing of the manuscripts. This work was supported in part by grants AM-02131, General Research Support SS0-1- FR-05479 (P.P.N.), HE-03299, HE-05209, and a National Heart Institute Research Career Award (D.K. ), K6-HE-734, from the National Institutes of Health, United States Public Health Service. P.P.N. Baltimore, Maryland D.K.

Keywords

alcohol chemistry metabolism physiology

Editors and affiliations

  • Padmanabhan P. Nair
    • 1
  • David Kritchevsky
    • 2
  1. 1.Biochemistry Research Division Department of MedicineSinai Hospital of Baltimore, Inc.BaltimoreUSA
  2. 2.The Wistar InstitutePhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4757-0647-5
  • Copyright Information Springer-Verlag US 1971
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-0649-9
  • Online ISBN 978-1-4757-0647-5
  • About this book