A General Update

  • Mauro Bendinelli
  • Herman Friedman

Part of the Infectious Agents and Pathogenesis book series (IAPA)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Brian W. J. Mahy
    Pages 1-18
  3. Nando K. Chatterjee
    Pages 35-50
  4. Richard L. Crowell, Burton J. Landau, Kuo-Hom Lee Hsu, Maggie Schultz
    Pages 51-63
  5. Ferdinando Dianzani, Maria R. Capobianchi, Donatella Matteucci, Mauro Bendinelli
    Pages 65-80
  6. Mauro Bendinelli, Pier Giulio Conaldi, Donatella Matteucci
    Pages 81-102
  7. Sally Ann Huber
    Pages 103-116
  8. Charles J. Gauntt
    Pages 159-179
  9. David P. Schnurr, Nathalie J. Schmidt
    Pages 181-201
  10. Rüdiger Dörries
    Pages 203-219
  11. Norman R. Grist, Daniel Reid
    Pages 221-239
  12. Milagros P. Reyes, A. Martin Lerner
    Pages 253-270
  13. Kirk W. Beisel, Noel R. Rose
    Pages 271-292
  14. Eleanor J. Bell, Fakhry Assaad, Karin Esteves
    Pages 319-337
  15. Giovanni Rocchi, Antonio Volpi
    Pages 339-349
  16. Antonio Toniolo, Giovanni Federico, Fulvio Basolo, Takashi Onodera
    Pages 351-382
  17. G. Hammond
    Pages 383-398
  18. Mark A. Pallansch
    Pages 399-417
  19. Back Matter
    Pages 419-430

About this book


It is now just 40 years since coxsackieviruses were first isolated by Dalldorf and Sickles in the "eponymous" town of Coxsackie, New York. Yet the overall contribution of coxsackieviruses to clinically evident dis­ ease of humans is still largely an open problem. Following their discov­ ery, coxsackieviruses were under intense clinical and laboratory scrutiny for a long time. Because of their relationship to polioviruses, the under­ standing of their structure, biochemistry, biology, and epidemiology ad­ vanced rapidly as a result of the formidable efforts that eventually led to the defeat of poliomyelitis. The ability of these viruses to infect mice permitted dissection of their pathogenicity in an experimental host and elucidation of conditions that influence its expression. Coxsackieviruses have been progressively associated with an increasing array of widely diverse human diseases. However, only some of the suggested causal correlations have been substantiated with satisfactory certainty. For others, conclusive evidence has so far resisted investigation. Most impor­ tant, among the latter are chronic maladies, such as dilated car­ diomyopathy and juvenile diabetes, that demand consideration. In recent times, there has been a partial eclipse of the subject of coxsackieviruses in the medical literature. In addition to the difficulties encountered in pinpointing their pathogenic potential, possible reasons include the general decline of interest in enteroviruses, which ensued after the conquest of poliomyelitis, and the continuous appearance in the limelight of new, more esoteric, and therefore more "appealing" viruses.


Antigen Pathogene Polypeptide Virus autoimmunity infection infections temperature viral infection

Editors and affiliations

  • Mauro Bendinelli
    • 1
  • Herman Friedman
    • 2
  1. 1.University of PisaPisaItaly
  2. 2.University of South FloridaTampaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-0249-1
  • Online ISBN 978-1-4757-0247-7
  • Series Print ISSN 1075-1289
  • Buy this book on publisher's site