Cerebral Sinus Thrombosis

Experimental and Clinical Aspects

  • Karl Einhäupl
  • Oliver Kempski
  • Alexander Baethmann

Table of contents

  1. Front Matter
    Pages i-viii
  2. Structural and Functional Basis

    1. Front Matter
      Pages 1-1
    2. M. Deckert, K. Frerichs, P. Mehraein, O. Kempski, A. Baethmann, K. Einhäupl
      Pages 39-42
    3. S. Kannuki, J. Cervos-Navarro, K. Matsumoto, Y. Nakagawa
      Pages 43-52
    4. K. Frerichs, M. Deckert, O. Kempski, K. Einhäupl, A. Baethmann
      Pages 53-58
  3. Mechanisms of Brain Tissue Damage

    1. Front Matter
      Pages 59-59
    2. P. Schmiedek, K. Einhäupl, E. Moser, U. Büll, G. Leinsinger, T. Kreisig
      Pages 75-83
    3. J. Grote, G. Siegel
      Pages 85-92
    4. O. Kempski, F. Staub, G.-H. Schneider, M. Zimmer, A. Baethmann
      Pages 93-104
    5. U. Heinemann, J. Sarvey
      Pages 105-122
  4. Clinical Aspects of Sinus Vein Thrombosis

    1. Front Matter
      Pages 141-141
    2. K. M. Einhäupl, A. Villringer, R. L. Haberl, W. Pfister, M. Deckert, H. Steinhoff et al.
      Pages 149-155
    3. M. Jacewicz, F. Plum
      Pages 157-170
    4. A. Hartmann, J. Wappenschmidt, L. Solymosi, F. Brassel
      Pages 171-186

About this book

Introduction

Contrary to the neurological manifestations of arterial cerebral blood flow disturbances, respective conditions resulting fram obstruction of the cerebro-venous system are far less well understood. Hence, cerebral sinus vein thrombosis (CSVT) ranks prominently among the group of neglected diseases of the brain. This might be attributable (a) to the diagnostic difficulties of the disorder and (b) to the fact that CSVT is associated with a host of heterogeneous neurological symptoms which often are not specific for the underlying venous flow disorder. Another complicating aspect is that CSVT is a consequence of other diseases as disparate as focal infection, trauma, neoplasia, or a thrombosis disposition caused by oral contraceptive use. Although progress has been made in establishing the correct diagnosis of the syndrome, many problems remain as the discussions contained within this volume vividly demonstrate. The same is true for the present understanding of the pathophysiological basis of the disease, eg, concerning the cerebro-venous circulation, the hemodynamic and neuropathological consequences in particular. Part of these deficits may be attributed to a scarcity of solid experimental data due to the limited availability of animal models. However, relevant experimental models are required for an in-depth analysis of the pathophysiological mechanisms, eg, causing brain tissue damage in relationship with the topographical distribution of the venous flow obstruction and, most importantly, for the testing of specific methods of treatment.

Keywords

blood brain circulation diagnosis diseases distribution infection sinus thrombosis tissue trauma treatment

Editors and affiliations

  • Karl Einhäupl
    • 1
  • Oliver Kempski
    • 2
  • Alexander Baethmann
    • 1
  1. 1.Klinikum GrosshadernLudwig-Maximilians-UniversityMunichGermany
  2. 2.Institute for Neurosurgical PathophysiologyJohannes Gutenberg-UniversityMainzGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-8199-0
  • Copyright Information Springer Science+Business Media New York 1990
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-8201-0
  • Online ISBN 978-1-4684-8199-0
  • About this book