Pharmacological Intervention in the Aging Process

  • Jay Roberts
  • Richard C. Adelman
  • Vincent J. Cristofalo

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 97)

Table of contents

  1. Front Matter
    Pages i-xii
  2. James R. Gillette, Jack A. Hinson
    Pages 5-25
  3. Lewis Aronow
    Pages 27-46
  4. Daniel W. Nebert
    Pages 55-83
  5. Vernon R. Young
    Pages 85-110
  6. P. N. Magee
    Pages 133-146
  7. Edward G. Lakatta
    Pages 147-169
  8. A. Horita
    Pages 171-185
  9. James A. Clemens, Ray W. Fuller
    Pages 187-206
  10. Bernard A. Eskin
    Pages 207-224
  11. Edward J. Cafruny
    Pages 225-230
  12. Ralph L. Cooper, Steven Brandt, Markku Linnoila, Louise H. Greenberg, Robert K. Dix, Benjamin Weiss et al.
    Pages 243-320
  13. Lewis Aronow
    Pages 336-336
  14. Back Matter
    Pages 321-335

About this book

Introduction

In the nearly three years that have elapsed since our first Philadelphia Symposium on Aging, our activities and interactions have expanded. We spent no small amount of time discussing the selection of a timely topic for our next symposium. For the first symposium, a variety of topics relating to the study of aging, ranging from phenomena at the cellular level to phenomena in disease states, were selected for consideration. For the present symposium, we thought it more desirable to concentrate on one area only, in order to summarize available information, discover what shortcomings exist, and suggest new directions for research. The paucity of in­ formation on pharmacological studies in aging and the compelling necessity for these studies made it clear to us that the time was appropriate for a review of this subject matter. The approach was to consider topics related to the effects of aging on the basic properties of drug action and on the effectiveness of drugs used in the therapy of diseases in several organ systems. Furthermore, it was felt that by considering the various pharmacological methods of intervention in the aging process, greater insight into the nature of aging would emerge. For the symposium, we brought together 13 outstanding workers in the field of pharmacology to discuss the selected topics. We expect that the chapters will be informative to workers in pharmacology and in biomedical disciplines in general, as well as provide a firm foundation for future work in this exciting area.

Keywords

Biotransformation Hormone aging diseases drug drugs intervention lipide metabolism neuropharmacology organ pharmacokinetics pharmacology research therapy

Editors and affiliations

  • Jay Roberts
    • 1
  • Richard C. Adelman
    • 2
  • Vincent J. Cristofalo
    • 3
  1. 1.Medical College of Pennsylvania and Philadelphia Geriatric CenterUSA
  2. 2.Temple University Institute on Aging and Fels Research Institute and Philadelphia Geriatric CenterUSA
  3. 3.The Wistar Institute and Philadelphia Geriatric CenterUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-7793-1
  • Copyright Information Springer-Verlag US 1978
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-7795-5
  • Online ISBN 978-1-4684-7793-1
  • Series Print ISSN 0065-2598
  • About this book