Research in Congenital Hypothyroidism

  • François Delange
  • Delbert A. Fisher
  • Daniel Glinoer

Part of the NATO ASI Series book series (NSSA, volume 161)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Physiopathology

    1. Front Matter
      Pages 1-1
    2. Gabriella Morreale de Escobar, María Jesús Obregón, Francisco Escobar del Rey
      Pages 15-29
    3. Charles H. Emerson
      Pages 31-43
    4. Roger Ekins, Arun Sinha, Maria Ballabio, Mark Pickard, Michael Hubank, Zaidan al Mazidi et al.
      Pages 45-60
    5. Delbert A. Fisher, Daniel H. Polk
      Pages 61-77
    6. Maria Jesús Obregón, Carmen Ruiz de Oña, Francisco Escobar del Rey, Gabriella Morreale de Escobar
      Pages 79-94
    7. Jean H. Dussault
      Pages 95-102
  3. Etiology

    1. Front Matter
      Pages 109-109
    2. Nobuo Matsuura, Junji Konishi, Kenji Fujieda, Kenji Yuri, Shohei Harada, Kanji Kasagi et al.
      Pages 111-122
    3. Steven C. Boyages, Jan Willem Lens, Reindert D. van der Gaag, Glen F. Maberly, Creswell J. Eastman, Hemmo A. Drexhage
      Pages 123-133
    4. Luca Chiovato, Paolo Vitti, Claudio Marcocci, Gianfranco Fenzi, Lia Giusti, Ferruccio Santini et al.
      Pages 141-150
  4. Diagnosis

    1. Front Matter
      Pages 155-155
    2. John Lazarus, Ieuan Hughes, Peter Harper, Stephen Bamforth
      Pages 157-164
    3. Samuel Refetoff, Myriam Charbonneau, David H. Sarne, Junta Takamatsu, Jean H. Dussault
      Pages 165-172
    4. François Delange
      Pages 173-185
    5. A. M. Ermans, J. Verelst, J. P. Chanoine, F. Delange
      Pages 187-192
    6. M. Hassan, C. Garel, J. Leger, P. Czenichov
      Pages 193-198

About this book

Introduction

Systematic screening for congenital hypothyroidism in the newborn was introduced some 15 years ago. The main objective was the prevention of mental retardation due to thyroid hormone deficiency during the early months of life. During the past decade screening programs have become routine throughout most of the industrialized world and many questions relating to implementation, organization and quality control of such programs have been largely resolved. Preliminary IQ and neurological data have indicated that screening and early treatment do, in fact, prevent mental retardation. However, a number of scientific questions related to congenital hypothyroidism remain unanswered and extensive research activities are ongoing in the field. The objective of the organizers of the Brussels workshop was to focus almost exclusively on these current research aspects of the screening programs. This workshop is the third international conference specifically devoted to neonatal thyroid screening. The first was held in La Malbaie in Quebec in the fall of 1979. That meeting was well organized and highly productive. Its proceedings constitute a bible in the field. After the Quebec meeting, we witnessed major and rapid advances in our understanding of neonatal thyroid physiology as well as screening methodology, organiza­ tion, data management, the significance of an approach to false negative and false positive results,patient follow-up, and assessment of follow-up and treatment, and the psychoneurological evaluation of affected infants. Some of these aspects were further developed during a second highly pro­ ductive international conference organized in Tokyo in 1982.

Keywords

assessment fetus hormone management methodology nutrition organizations pathology physiology prevention quality research screening thyroid hormone treatment

Editors and affiliations

  • François Delange
    • 1
  • Delbert A. Fisher
    • 2
  • Daniel Glinoer
    • 1
  1. 1.University of BrusselsBrusselsBelgium
  2. 2.Harbor-UCLA Medical CenterUniversity of California, Los AngelesTorranceUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-7580-7
  • Copyright Information Springer-Verlag US 1989
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-7582-1
  • Online ISBN 978-1-4684-7580-7
  • About this book