Molecular Pathogenesis of Gastrointestinal Infections

  • T. Wadström
  • P. H. Mäkelä
  • A.-M. Svennerholm
  • H. Wolf-Watz

Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 58)

Table of contents

  1. Front Matter
    Pages i-x
  2. The Mucosal Surface

    1. Robert W. Lobley
      Pages 1-8
    2. Karl-Anders Karlsson, Jonas Ångström, Susann Teneberg
      Pages 9-21
    3. Ingemar Carlstedt, Stefan Elmquist, Ingela Ljusegren, Gunnar C. Hansson
      Pages 23-28
    4. Paul S. Cohen, Beth A. McCormick, David P. Franklin, Robert L. Burghoff, David C. Laux
      Pages 29-31
    5. Tore Midtvedt, Göran Larson, Catharina Svanborg
      Pages 33-36
  3. The Parasite

    1. Bernt Eric Uhlin, Björn Dagberg, Kristina Forsman, Mikael Göransson, Birgit Knepper, Peter Nilsson et al.
      Pages 55-58
    2. Wim Gaastra, Anja M. Hamers, Bart J. A. M. Jordi, Paul H. M. Savelkoul, Geraldine A. Willshaw, Moyra M. McConnell et al.
      Pages 61-70
    3. Heinz Hoschützky, Thomas Bühler, Ralph Ahrens, Klaus Jann
      Pages 71-78
    4. Per Klemm, Karen A. Krogfelt
      Pages 87-92
    5. Inga Benz, M. Alexander Schmidt
      Pages 103-105
  4. Enterotoxigenic Organisms

    1. J. Holmgren, S. J. S. Hardy, T. R. Hirst, S. Johansson, G. Jonson, J. Sanchez et al.
      Pages 115-124
    2. Yoshifumi Takeda, Shinji Yamasaki, Toshiya Hirayama, Yasutsugu Shimonishi
      Pages 125-138

About this book


The meeting that provided the material for this book was the 58th Symposium of the Federation of European Microbiological Societies (FEMS) entitled MOLECULAR PATHOGENESIS OF GASTROINTESTINAL INFECTIONS which was held in Helsingor, Denmark from 2nd to 4th September, 1990. The aim of this meeting was to bring together scientists from a range of discipline- microbiology, cell biology, molecular biology and immunology - to consider how microbes, including parasites, colonize and infect the gastrointestinal tract. The programme was designed to focus particular attention on the range of strategies whereby enterovirulent bacteria and parasites colonize the gastrointestinal mucin layer, how they adhere to and penetrate the epithelial layer by entering the cells or passing between them, and how various protein toxins may facilitate these processes. Speakers were especially encouraged to highlight the recent expansion in our knowledge of the molecular mechanisms by which enterotoxigenic and enteropathogenic Escherichia coli, shigellae, salmonellae and Yersinia enterocolitica cause intestinal disease. There were also discussions of recently-discovered gastrointestinal pathogens such as Clostridium difficile and Helicobacter pylori as well as accounts of how virulent determinants can be used to develop new diagnostic methods based on DNA gene probes and the polymerase chain reaction (PCR). These presentations provided the basis for the chapters in this book.


Cytosol Flora Pathogene Toxin development microbe microbiology polymer protein transcription virus

Editors and affiliations

  • T. Wadström
    • 1
  • P. H. Mäkelä
    • 2
  • A.-M. Svennerholm
    • 3
  • H. Wolf-Watz
    • 4
  1. 1.University of LundLundSweden
  2. 2.National Public Health InstituteHelsinkiFinland
  3. 3.University of GothenburgGothenburgSweden
  4. 4.University of UmeåUmeåSweden

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1991
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5984-5
  • Online ISBN 978-1-4684-5982-1
  • About this book