Medical Virology 9

1. Front Matter

   Pages i-x

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2. Evaluation of Immunoassays for Electron Microscopy

   • Frances W. Doane, Nan Anderson, Francis Lee, Kathryn Pegg-Feige, John Hopley

   Pages 1-16

3. Monoclonal Time-Resolved Fluoroimmunoassay: Sensitive Systems for the Rapid Diagnosis of Respiratory Virus Infections

   • John C. Hierholzer, Larry J. Anderson, Pekka E. Halonen

   Pages 17-45

4. The Use of the Polymerase Chain Reaction in the Detection, Quantification and Characterization of Human Retroviruses

   • Bernard J. Poiesz, Garth D. Ehrlich, Bruce C. Byrne, Keith Wells, Shirley Kwok, John Sninsky

   Pages 47-75

5. Round Table: Polymerase Chain Reaction (PCR)

   • Luis M. de la Maza, Ellena M. Peterson

   Pages 77-84

6. Clinical Serological and Intestinal Immune Responses to Rotavirus Infection of Humans

   • Ruth Bishop, Jennifer Lund, Elizabeth Cipriani, Leanne Unicomb, Graeme Barnes

   Pages 85-110

7. Medical Virology of Small Round Gastroenteritis Viruses

   • Neil R. Blacklow

   Pages 111-128

8. Rabies — New Challenges by an Ancient Foe

   • Richard W. Emmons

   Pages 129-145

9. HTLV-I Infections

   • Yorio Hinuma

   Pages 147-161

10. Human Herpesvirus 6: Basic Biology and Clinical Associations

    • John A. Stewart

    Pages 163-186

11. Strains of Respiratory Syncytial Virus: Implications for Vaccine Development

    • Larry J. Anderson

    Pages 187-205

12. Plans for Human Trials of a Vaccine Against Epstein-Barr Virus Infection

    • M. A. Epstein

    Pages 207-215

13. Advances in the Treatment of HIV-1 Infections

    • Martin S. Hirsch

    Pages 217-236

14. Abstracts

    • A. Telenti, W. F. Marshall, J. Proper, A. J. Aksamit, T. F. Smith, S. Matthey et al.

    Pages 237-271

15. Back Matter

    Pages 273-286

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It would have been difficult at the beginning of the 80's to have predicted that by the end of the decade, Medical Virology would have become one of the most important topics in the area of both basic and clinical research. Although we were expecting a progressive increase in awareness of the role played by viruses in different diseases, we did not expect the outbreak of a fatal disease that was going to shake the roots of our society. The appearance of the human immunodeficiency virus (HIV-1) in the early 80's, has prompted a unique re­ search impetus in the area of Medical Virology. The knowledge that we are gaining in our attempt to understand the biology of HIV-1 and the immuno­ logical response to this virus should not only help us control the spread of this virus, but should also help us to better understand other viral infections. Let us hope that during the 1990's we can learn how to control HIV-1 infections so that by the end of the decade, no more human lives succumb to an infection with this virus. Luis M. de la Maza Irvine, California Ellena M. Peterson March, 1990 v ACKNO~EDGEMENTS We would like to thank all the speakers that came to San Francisco and shared their knowledge during the lectures and for writing the chapters in this book.

• immunodeficiency
• infection
• retroviruses
• vaccine
• virology
• virus

• Irvine Medical Center, University of California, Orange, USA

  Luis M. Maza, Ellena M. Peterson

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