Cell Calcium Metabolism

Physiology, Biochemistry, Pharmacology, and Clinical Implications

  • Gary Fiskum

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Transport and Pharmacology

    1. Front Matter
      Pages 1-1
    2. Sophie Lotersztajn, Catherine Pavoine, Ariane Mallat, Dominique Stengel, Paul Insel, Françoise Pecker
      Pages 3-11
    3. Ernesto Carafoli
      Pages 21-26
    4. John P. Reeves, Joo Cheon
      Pages 27-31
    5. William A. Catterall, Michael J. Seagar, Masami Takahashi, Benson M. Curtis
      Pages 33-45
    6. Michel Fosset, Sylvie Vandaele, Jean-Pierre Galizzi, Jacques Barhanin, Michel Lazdunski
      Pages 47-56
    7. Pal L. Vaghy, Kunihisa Miwa, Kiyoshi Itagaki, Ferenc Guba Jr., Edward McKenna, Arnold Schwartz
      Pages 57-64
    8. Christy L. Cooper, Cliff M. O’Callahan, M. Marlene Hosey
      Pages 65-73
    9. Anibal E. Vercesi, Lucia Pereira-Da-Silva, Ione S. Martins, Eva G. S. Carnieri, Celene F. Bernardes, Marcia M. Fagian
      Pages 103-111
  3. Phosphoinositide Metabolism

    1. Front Matter
      Pages 113-113
    2. Michael John Berridge
      Pages 115-124
    3. John R. Williamson, Roy A. Johanson, Carl A. Hansen, Jonathan R. Monck
      Pages 125-141
    4. C. J. Kirk, J. B. Parry, R. F. Irvine, R. H. Michell, S. B. Shears
      Pages 143-148
    5. Donald L. Gill, Julienne M. Mullaney, Tarun K. Ghosh, Sheau-Huei Chueh
      Pages 157-167

About this book

Introduction

A widespread appreciation for the role that calcium plays in cell physiology and patho­ physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D. C. The participants in this unique meeting rep­ resented diverse fields of basic and clinical research, such as molecular physiology, oncology, molecular genetics, cardiology, bioenergetics, pathology, and endocrinology. The content of the proceedings of the symposium represents work in these and other areas of biomedical research. Organization of the book is aimed at striking a balance between the biochemistry 2 and physiology of normal cell Ca + metabolism and the pathological consequences of al­ 2 terations in cell Ca + homeostasis. The first section of the book is devoted to the transport mechanisms responsible for 2 2 regulating intracellular Ca + and the pharmacological modalities for controlling cell Ca + . Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels. The second section covers the exciting relationships between phosphoinositide metab­ 2 olism, signal transduction, and cell Ca + metabolism. This section begins with an eloquent overview by Professor Michael Berridge, who was the keynote speaker at the symposium and the recipient of the scientific merit award.

Keywords

ATP Calcium biochemistry chemistry clinical research endocrinology genetics membrane membrane transport metabolism molecular genetics physiology research signal transduction

Editors and affiliations

  • Gary Fiskum
    • 1
  1. 1.Departments of Biochemistry and Emergency MedicineThe George Washington University School of Medicine and Health SciencesUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-5598-4
  • Copyright Information Springer-Verlag US 1989
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5600-4
  • Online ISBN 978-1-4684-5598-4
  • About this book