Risk Assessment and Decision Making Using Test Results

The Carcinogenicity Prediction and Battery Selection Approach

  • Julia Pet-Edwards
  • Yacov Y. Haimes
  • Vira Chankong
  • Herbert S. Rosenkranz
  • Fanny K. Ennever

Table of contents

  1. Front Matter
    Pages i-viii
  2. Basics of the CPBS Approach to Risk Assessment and Decision Making

    1. Front Matter
      Pages 1-1
    2. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 3-14
    3. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 15-63
  3. Carcinogenicity Prediction and Battery Selection Methodology

    1. Front Matter
      Pages 65-66
    2. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 67-123
    3. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 125-164
    4. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 165-173
    5. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 175-202
  4. Epilogue

    1. Julia Pet-Edwards, Yacov Y. Haimes, Vira Chankong, Herbert S. Rosenkranz, Fanny K. Ennever
      Pages 203-205
  5. Back Matter
    Pages 207-211

About this book

Introduction

The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields­ engineering, epidemiology, chemistry, etc. These difficulties are particularly common in problems that have dynamic and stochastic characteristics driven by multiple purposes and goals, with complex interconnections and inter­ dependencies. Acquiring an appropriate data base, processing and analyzing model results, and transmitting these results at an appropriate technical, social, political, and institutional level are additional difficulties that must be addressed. This book is grounded on the premise that risks are best assessed on the basis of experimental results and sound mathematical analyses, coupled with the knowledge of experts. The carcinogenicity prediction and battery selection (ePBS) approach described herein provides a systematic mechan­ ism-a synthesis of systems and statistical and decision analyses-to aid researchers and decision makers in the critical field of carcinogenicity prediction in selecting an appropriate battery of tests to use and in translating experimental results into information that can be used as an aid to decision making.

Keywords

battery chemistry decision making engine information interconnect model processing research risk risk assessment sound

Authors and affiliations

  • Julia Pet-Edwards
    • 1
  • Yacov Y. Haimes
    • 1
  • Vira Chankong
    • 2
  • Herbert S. Rosenkranz
    • 2
  • Fanny K. Ennever
    • 2
  1. 1.University of VirginiaCharlottesvilleUSA
  2. 2.Case Western Reserve UniversityClevelandUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-5595-3
  • Copyright Information Springer-Verlag US 1989
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5597-7
  • Online ISBN 978-1-4684-5595-3
  • About this book