Immunological Approaches to Contraception and Promotion of Fertility

  • G. P. Talwar

Part of the Reproductive Biology book series (RBIO)

Table of contents

  1. Front Matter
    Pages i-x
  2. Craig K. Wallace
    Pages 1-2
  3. Duane Alexander
    Pages 3-4
  4. Roy Hertz
    Pages 5-15
  5. N. C. Sharma, Om Singh, Amitabh Gaur, D. N. Rao, Vinod Singh, L. V. Rao et al.
    Pages 37-41
  6. Vemuri B. Reddy, Anton K. Beck, Vincent Vellucci, Anthony J. Garramone, Edward G. Bernstine
    Pages 77-91
  7. William W. Chin, Soheyla D. Gharib
    Pages 93-102
  8. N. R. Moudgal, G. S. Murthy, A. J. Rao, N. Ravindranath, M. R. Sairam, S. G. Kotagi et al.
    Pages 103-110
  9. C. Shaha, S. Kaul, M. Kini, M. Chowdhury, R. Anand, C. Das et al.
    Pages 143-150
  10. Anthony R. Bellvé, Stuart B. Moss, Michael J. Donovan, Marion C. Usselman
    Pages 155-174

About this book


Contraceptive research has entered the new age of vaccines. Realistic prospects exist for the development of an entirely new battery of vaccines for use in human and veterinary medicine. Among them may be anti-fertility vaccines, based on physiological mechanisms applicable to either the female or male. This volume is a comprehensive review - a status report - of the subjects including fundamental work on the search for useful epitopes and ranging to applied vaccinology. One vaccine to prevent pregnancy, for use by women, has already been studied extensively. G.P. Talwar, the volume's editor and his colleagues in New Oelhi, India, published in 1976 a landmark series of papers describing the immunological properties of a preparation consisting of the alum-precipitated beta-subunit of human chorionic gonadotropin (hCG) chemically linked to tetanus toxoid. The principle of enhancing antigenicity of a self-protein by linkage of the epitope to a carrier protein was employed and tested clinically. These trials, carried out under the auspices of the Indian Council for Medical Research, were the first application of the carrier protein concept for a vaccine for human use. The encouraging results stimulated a wave of research not only on the use of hCG-based vaccines, but on other antigens as well.


Embryo cloning development fertility medicine paper protein vaccine wave

Editors and affiliations

  • G. P. Talwar
    • 1
  1. 1.National Institute of ImmunologyNew DelhiIndia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1986
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5142-9
  • Online ISBN 978-1-4684-5140-5
  • About this book