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Movement Disorders

  • Nandkumar S. Shah
  • Alexander G. Donald

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Introduction Neuropharmacology of Movement Disorders

  3. Parkinson’s Disease

    1. Front Matter
      Pages 37-37
    2. Richard P. Newman, Donald B. Calne
      Pages 39-52
    3. Abraham N. Lieberman, Menek Goldstein
      Pages 83-102
  4. Tardive Dyskinesia

    1. Front Matter
      Pages 117-117
    2. Jes Gerlach, Daniel E. Casey, Søren Korsgaard
      Pages 119-147
    3. Dilip V. Jeste, Charles A. Kaufmann, Richard Jed Wyatt
      Pages 149-157
    4. Edmond H. Pi, George M. Simpson
      Pages 181-193
    5. George Gardos, Jonathan O. Cole
      Pages 195-204
    6. Larry D. Alphs, John M. Davis
      Pages 205-226
  5. Tourette Syndrome and Tic

    1. Front Matter
      Pages 227-227
    2. Elaine Shapiro, Arthur K. Shapiro
      Pages 229-245
    3. James F. Leckman, Donald J. Cohen, R. Arlen Price, Mark A. Riddle, Ruud B. Minderaa, George M. Anderson et al.
      Pages 257-272
  6. Huntington’s Disease

    1. Front Matter
      Pages 273-273
    2. Richard L. Borison, Ana Hitri, Bruce I. Diamond
      Pages 275-292
    3. Charles N. Still, Thomas J. Goldschmidt
      Pages 293-306
  7. Neuroleptic Drugs in the Production of Movement Disorders

    1. Front Matter
      Pages 307-307
    2. Christopher G. Goetz, Harold L. Klawans, Caroline M. Tanner
      Pages 309-321
    3. Thomas R. E. Barnes, Malcolm P. I. Weller
      Pages 323-341
    4. J. M. S. Pearce, C. C. Clough
      Pages 343-364
    5. Daniel Tarsy, Ross J. Baldessarini
      Pages 365-389
  8. Back Matter
    Pages 397-406

About this book

Introduction

The human nervous system-that most complex organization of energy and matter-has yielded a few glimmers of understanding of its operational me­ chanics during the last two decades. These have mostly been at the biochemical level of structure and function. Throughout history, as one of the mysteries of nature begins to yield some insights into its function, it has been beneficial to look at it from different points of view. We have developed a volume on movement disorders that is primarily directed toward the biochemical understanding of these disorders and their treatment. Each disorder is presented from several points of view. Although this approach leads to some repetition, it is our aim that the final outcome be a more complete understanding. Much has been written about movement: the beauty of the prima ballerina, the strength of the olympic athlete, and the agility of the surgeon. Seldom do we stop to look beneath the surface-the coordination of muscle groups, the finely tuned balance allowing rapid response in either direction, the individual muscle fibers coordinated to maximize strength and agility, and the nerve fibers connecting muscle with nerve centers. Some of these communicate sensory input of position to the centers while others communicate directions of move­ ment to muscles. We encourage our readers to be constantly alert to the possibility of in­ creasing their understanding of other nervous system functions, including thought disorder, through an understanding of movement, either in general principle or by specific chemical interaction.

Keywords

Parkinson Syndrom brain clonidine epidemiology muscle nervous system neuropharmacology pathophysiology pharmacology physiology prevention schizophrenia syndromes therapy

Editors and affiliations

  • Nandkumar S. Shah
    • 1
    • 2
  • Alexander G. Donald
    • 2
    • 3
  1. 1.Ensor Foundation Research LaboratoryWilliam S. Hall Psychiatric InstituteColumbiaUSA
  2. 2.Department of Neuropsychiatry and Behavioral ScienceUniversity of South Carolina School of MedicineColumbiaUSA
  3. 3.William S. Hall Psychiatric InstituteColumbiaUSA

Bibliographic information