Hybridoma Technology in the Biosciences and Medicine

  • Timothy A. Springer
Book

Table of contents

  1. Front Matter
    Pages i-xxv
    PDF

  2. The Production and Improvement through Genetic Engineering of Monoclonal Antibodies

    1. Front Matter
      Pages 1-1
      PDF
    2. Monoclonal Antibody Strategy and Techniques
      Zelig Eshhar
      Pages 3-41
    3. Strategies for Production of Human Monoclonal Antibodies
      Susan P. C. Cole, Danuta Kozbor, John C. C. Roder
      Pages 43-55
    4. The Antibody Combining Site
      Edgar Haber, Jiří Novotný
      Pages 57-76
    5. The Generation of Better Monoclonal Antibodies through Somatic Mutation
      Gad Spira, Antonio Bargellesi, Roberta R. Pollock, Hector L. Aguila, Matthew D. Scharff
      Pages 77-88
    6. Switching the Isotype of Monoclonal Antibodies
      Thomas J. Kipps
      Pages 89-101
    7. The Analysis of Structural Diversity in the Antibody Response
      Gillian M. Griffiths, Cesar Milstein
      Pages 103-115
    8. Expression of Cloned Immunoglobulin Genes
      Frederick W. Alt
      Pages 117-134

  3. Monoclonal Antibodies in Biomedical Research: Principles and Applications

    1. Front Matter
      Pages 135-135
      PDF
    2. The Immunochemistry of Monoclonal Antibodies: Studies on One Immunologic Supergene (HLA) with the Products of Another
      Peter Parham
      Pages 137-161
    3. Purification of Membrane Glycoproteins with Monoclonal Antibody Affinity Columns
      Pauline Johnson, Alan F. Williams, Gillian R. Woollett
      Pages 163-175
    4. Transferrin Receptor
      Ian S. Trowbridge
      Pages 177-189
    5. Functional and Structural Interrelationships among the Mac-1, LFA-1 Family of Leukocyte Adhesion Glycoproteins, and their Deficiency in a Novel Heritable Disease
      Timothy A. Springer, Donald C. Anderson
      Pages 191-206
    6. Demonstration of Receptor Function of Membrane Proteins by Selection and Immobilization with Monoclonal Antibodies
      Janis Jacks Weis, Douglas T. Fearon
      Pages 207-221
    7. Production of Rat × Mouse Hybridomas for the Study of the Nicotinic Acetylcholine Receptor
      Susan M. Hochschwender, Lorene K. Langeberg, Douglas W. Schneider, Jon M. Lindstrom
      Pages 223-228
    8. Sperm Surface Domains
      Diana G. Myles, Paul Primakoff
      Pages 239-250
    9. The Cytoskeleton
      Lan Bo Chen, Sharon Rosenberg, Karen K. Nadakavukaren, Elizabeth S. Walker, Elizabeth L. Shepherd, Glenn D. Steele Jr.
      Pages 251-268
    10. Monoclonal Antibodies as Molecular Probes of the Nervous System
      Colin J. Barnstable
      Pages 269-289
    11. Application of Monoclonal Antibodies to Issues of Plasma Lipoprotein Structure and Function
      Linda K. Curtiss
      Pages 291-308

About this book

Keywords

antibody antigen antigen presentation genetics immunoglobulin immunotherapy interferon lymphocytes proteins transplantation virus

Editors and affiliations

  • Timothy A. Springer
    • 1
  1. 1.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-4964-8
  • Copyright Information Springer-Verlag US 1985
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-4966-2
  • Online ISBN 978-1-4684-4964-8
  • About this book