Neurotransmitter Actions in the Vertebrate Nervous System

  • Michael A. Rogawski
  • Jeffery L. Barker

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Amino Acids

    1. Front Matter
      Pages 1-1
    2. Robert A. Davidoff, John C. Hackman
      Pages 3-32
    3. B. E. Alger
      Pages 33-69
    4. Jeffery L. Barker
      Pages 71-100
    5. Andrea Nistri
      Pages 101-123
    6. Mark L. Mayer, Gary L. Westbrook
      Pages 125-139
  3. Acetylcholine

    1. Front Matter
      Pages 141-141
    2. John S. Kelly, Michael A. Rogawski
      Pages 143-197
  4. Biogenic Amines

    1. Front Matter
      Pages 199-199
    2. C. P. VanderMaelen
      Pages 201-240
    3. Michael A. Rogawski
      Pages 241-284
    4. Anthony A. Grace, Benjamin S. Bunney
      Pages 285-319
    5. Helmut L. Haas
      Pages 321-337
  5. Neuropeptides

    1. Front Matter
      Pages 339-339
    2. Raymond Dingledine
      Pages 341-364
    3. Shiro Konishi
      Pages 365-384
    4. Nae J. Dun
      Pages 385-410
    5. John R. Delfs, Marc A. Dichter
      Pages 411-437
    6. Michel Mühlethaler, Mario Raggenbass, J. J. Dreifuss
      Pages 439-458
    7. Yuh Nung Jan, Lily Yeh Jan
      Pages 459-478
  6. Adenosine and ATP

    1. Front Matter
      Pages 479-479
    2. Donald A. McAfee, Barbara K. Henon
      Pages 481-502
  7. Back Matter
    Pages 503-511

About this book


Intercellular communication via bioactive substances occurs in virtually all multicellular systems. Chemical neurotransmission in the vertebrate nervous system represents a form of signaling of this type. The biology of chemical neurotransmission is complex, involving transmitter synthesis, transport, and release by the presynaptic neuron; signal generation in the target tissue; and mechanisms for termination of the response. The focus of this book is on one aspect of this scheme: the diverse electrophysiological effects induced by different neurotransmitters on targets cells. In recent years, astonishing progress has been made in elucidating the specific physiological signals mediated by neurotransmitters in the verte­ brate nervous system, yet, in our view, this has not been adequately recog­ nized, perhaps because the new concepts have yet to filter into neuroscience textbooks. Nevertheless, the principles of neurotransmitter action are critical to advances in many areas of neuroscience, including molecular neurobiol­ ogy, neurochemistry, neuropharmacology, physiological psychology, and clinical neuroscience. It was the need for a sourcebook that prompted us to engage a group of neurophysiologists to prepare the chapters in this volume. However, there was an additional reason for this book: more and more it seemed that the field, if not yet having reached maturity, at least was ap­ proaching adolescence, with strengths in some areas and healthy conflicts in others. At this stage of development a textbook can help to define a field, clarify problems to be resolved, and identify areas for future investigation.


adenosine brain brainstem muscle nervous system neurochemistry neurons neuropeptides neuropharmacology neuroscience spinal cord

Editors and affiliations

  • Michael A. Rogawski
    • 1
  • Jeffery L. Barker
    • 1
  1. 1.National Institute of Neurological and Communicative Disorders and StrokeNational Institutes of HealthBethesdaUSA

Bibliographic information