Immune Complexes and Human Cancer

  • Fernando A. Salinas
  • Michael G. HannaJr.

Part of the Contemporary Topics in Immunobiology book series (CTI, volume 15)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Fernando A. Salinas, Kian H. Wee, Hulbert K. Silver
    Pages 55-109
  3. Terence M. Phillips, Thomas V. Holohan, Stefan Korac, Newton S. More, William D. Queen
    Pages 111-137
  4. Didier Cupissol, Christian Thierry, Bernard C. Serrou
    Pages 139-146
  5. Karl Erik Hellström, Ingegerd Hellström, Harry W. Snyder Jr., Joe P. Balint, Frank R. Jones
    Pages 213-238
  6. Mehmet F. Fer, Robert K. Oldham
    Pages 257-276
  7. Back Matter
    Pages 277-280

About this book


Immune Complexes and Human Cancer, the fifteenth volume of Contem­ porary Topics in Immunobiology, is a compilation of information derived from recent studies on the role of circulating immune complexes (CIC) in the patho­ genic manifestations of a variety of human cancers. Technical improvements in the detection of CIC in body fluids have resulted in data that indicate that CIC do occur in different types of cancer. In addition, tumor-associated antigens and antibodies have been detected in immune complexes of cancer patients' sera. Until recently the exact role and clinical relevance of immune complexes have been the subject of debate, partially because of the problems encountered in measuring immune complexes. But these problems are being confronted as more accurate measurement protocols are developed. Technical refinements, along with strict protocols, have provided evidence of heterogeneity in CIC, a factor that makes accurate detection of immune complexes in cancer patients difficult. Recent insights indicate that the measurement of immune complexes in cancer patients may be clinically useful not only as a tumor marker, but also in regard to the deranged immune response of tumor-bearing hosts and other disorders such as nephrotic syndrome, immune anemias, and clotting dysfunction.


anemia antibody antigen cancer immune response immunobiology tumor

Editors and affiliations

  • Fernando A. Salinas
    • 1
    • 2
  • Michael G. HannaJr.
    • 3
  1. 1.Cancer Control Agency of British ColumbiaVancouverCanada
  2. 2.University of British ColumbiaVancouverCanada
  3. 3.Litton Institute of Applied BiotechnologyRockvilleUSA

Bibliographic information