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Human in Vitro Fertilization and Embryo Transfer

  • Don P. Wolf
  • Martin M. Quigley

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Martin M. Quigley
    Pages 37-46
  3. Julane Hotchkiss
    Pages 47-57
  4. Cecilia L. Schmidt
    Pages 59-79
  5. Pedro J. Beauchamp
    Pages 133-148
  6. Pedro J. Beauchamp
    Pages 149-169
  7. Jeffrey Boldt, Don P. Wolf
    Pages 171-211
  8. William Byrd, Don P. Wolf
    Pages 213-273
  9. Don P. Wolf, Joseph E. Sokoloski
    Pages 297-326
  10. Cecilia L. Schmidt
    Pages 327-340
  11. Paul D. Webb, Stanley R. Glasser
    Pages 341-364
  12. Back Matter
    Pages 425-440

About this book

Introduction

The births of more than 100 apparently normal infants at term following pregnancies initiated by in vitro fertilization and embryo transfer testifies to the successful clinical application of insights obtained from studies in reproductive biology over the last 20 years. In women, these studies have included: 1) characterization of the changes in blood hormone profiles throughout ovulatory menstrual cycles; 2) documentation of the hormonal composition of antral fluid in developing and degenerating preovulatory follicles; 3) correlation of these observations with the state of oocyte maturation and the fertilizability of the oocyte; 4) application of pharmacologic agents for perturbing the normal hormone profiles to regulate the number of preovulatory follicles developing and the time of ovulation; and 5) development of non-invasi ve methods for monitoring follicular development. Optimizing methods for maturing and fertilizing eggs, for moni toring normal development in vi tro, and for transferring and achieving implantation of embryos are continuing concerns of physicians and scientists responsible for extant programs. In addition, all serious students of reproductive biology should critically examine every facet of the processes which must concatenate to assure birth of normal infants following pregnancies achieved by these methods. However, the literature which contains the informational substrate is dispersed widely in a plethora of journals not always readily accessible. Bringing the essentials together facilitates both rapid retrieval of data and access to relevant literature.

Keywords

Embryo biology fertility implantation pharmacology

Editors and affiliations

  • Don P. Wolf
    • 1
  • Martin M. Quigley
    • 1
  1. 1.University of Texas Health Science CenterHoustonUSA

Bibliographic information