Immunobiology of Proteins and Peptides—II

  • M. Z. Atassi

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 150)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Molecular Aspects of T- and B-Cell Recognition of Protein Antigens

    1. Front Matter
      Pages 1-1
    2. Robert H. Swanborg, James H. Holda, Joyce A. Killen
      Pages 3-22
    3. N. R. Rose, M. Accavitti, E. F. Pydyn, M. A. Leon, R. K. Brown
      Pages 23-35
    4. Charles Hannum, Michiel Ultee, Louis A. Matis, Ronald H. Schwartz, E. Margoliash
      Pages 37-51
    5. Charles A. Janeway Jr., Kim Bottomly, Barry Jones, Patricia P. Jones, Ethan A. Lerner, Louis A. Matis et al.
      Pages 53-71
  3. Genetic Control of the Immune Response to Proteins and Peptides

    1. Front Matter
      Pages 95-95
    2. Christopher J. Krco, A. Latif Kazim, M. Zouhair Atassi, Chella S. David
      Pages 127-140
  4. Regulation of the Immune Response

    1. Front Matter
      Pages 157-157
    2. A. J. Infante, M. Z. Atassi, C. G. Fathman
      Pages 159-167
    3. Neal Roehm, John Kappler, Philippa Marrack
      Pages 169-182
    4. David W. Scott, P. S. Pillai, Scott J. Anderson, Ronald B. Corley
      Pages 183-200
    5. Joel W. Goodman, Danute E. Nitecki, Sherman Fong, Zehra Kaymakcalan
      Pages 219-225
  5. Back Matter
    Pages 227-230

About this book

Introduction

The immune response is largely dependent on molecular inter­ actions involving proteins. The recognition of antigen molecules, whether they are proteins or non-proteins, whether they are self or non-self, takes place at the molecular-cellular interface through membrane receptor molecules that are proteins. The initial step of recognition activates a complex series of cellular events requiring some mechanism of cell-cell interactions and communi­ cations, eventually leading to antibody production. This biolo­ gical cascade is controlled at several positions along its con­ secutive pathways by protein molecules, either in the free form or as receptors on membranes of cells committed to this activity. Clearly, then, the proper understanding of the response by cells of the immune system will depend, to a great measure, on the definition of the molecular events involving protein interactions. Obviously, cells work via molecules and molecules work via cells and, at this level of functional resolution, molecular immunology and cellular immunology will merge and will depend heavily on protein chemistry.

Keywords

antibody antigen immune response immune system immunobiology immunology proteins

Editors and affiliations

  • M. Z. Atassi
    • 1
  1. 1.Mayo ClinicRochesterUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-4331-8
  • Copyright Information Springer-Verlag US 1982
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-4333-2
  • Online ISBN 978-1-4684-4331-8
  • Series Print ISSN 0065-2598
  • About this book