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The Endometrium

Hormonal Impacts

  • Jean de Brux
  • Rodrigue Mortel
  • Jean Pierre Gautray

Table of contents

  1. Front Matter
    Pages i-viii
  2. Jean Pierre Gautray
    Pages 1-13
  3. Dominique Martel, Catherine Malet, Jean Pierre Gautray, Alexandre Psychoyos
    Pages 15-29
  4. Paul Robel, Rodrigue Mortel, Etienne Emile Baulieu
    Pages 43-61
  5. Viviane Casimiri, Alexandre Psychoyos
    Pages 63-79
  6. Robert Scholler, Khalil Nahoul, Catherine Blacker
    Pages 81-106
  7. Jean Pierre Gautray, Marie Charles Colin, Jean Paul Vielh, Jean de Brux
    Pages 123-143
  8. Rodrigue Mortel, Paul Robel, Etienne Emile Baulieu
    Pages 145-160
  9. Back Matter
    Pages 161-167

About this book

Introduction

Although the physiology of the menstrual cycle appears clear and easily explained by a balance in the concentration of various sex steroid hormones, numerous details of its mechanism are still poorly understood and little is known about the relationship among clinical events, plasma hormone concentrations, molecular impacts on target tissues and their regulation. In the following chapters, the authors have attempted to establish a correlation between endometrial histology and well-understood physiologic events of the menstrual cycle. They have provided up-to-date information on the effects of various hormones and combinations of hormones on the endometrium. The interdependence of endometrial morphology, molecular biology, endocrinology and physiology, provides grounds for a better understanding of the complex mechanism of the menstrual cycle, and sheds some light on its pathophysiology. Such an approach adds ariother dimension to interpretation of many menstrual abnormalities and numerous aspects of infertility in women with normal physiognomies and apparently regular menstrual cycles. The pathologist must be aware of these new concepts since a knowledge of functional changes reflected in hormone serum levels and sex steroid receptor concentrations allows a mare detailed analysis and a better interpretation of the structural features of the endometrium. This information placed in the proper clinical context can help the gynecologist provide optimal therapy. The reader will find a valuable reference for a synthesis of clinical, morphological, and biochemical data related to the menstrual cycle and its aberrations.

Keywords

Embryo Plasma biology endocrinology fertility histology molecular biology morphology physiology receptor regulation sex synthesis therapy tissue

Editors and affiliations

  • Jean de Brux
    • 1
  • Rodrigue Mortel
    • 2
  • Jean Pierre Gautray
    • 3
  1. 1.Foundation for Education and Research in Histo- and CytopathologyParisFrance
  2. 2.M. S. Hershey Medical CenterPennsylvania State UniversityHersheyUSA
  3. 3.University of Paris Val de MarneCreteilFrance

Bibliographic information