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The Heroin Stimulus

Implications for a Theory of Addiction

  • Roger E. Meyer
  • Steven M. Mirin

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Roger E. Meyer, Steven M. Mirin
    Pages 1-21
  3. Steven M. Mirin, Roger E. Meyer
    Pages 23-37
  4. Steven M. Mirin, Roger E. Meyer, Nancy M. Valentine
    Pages 39-59
  5. Roger E. Meyer, Steven M. Mirin
    Pages 61-91
  6. Steven M. Mirin, Roger E. Meyer
    Pages 93-118
  7. Thomas F. Babor, Steven M. Mirin, Roger E. Meyer
    Pages 119-135
  8. Roger E. Meyer, Joseph J. Schildkraut, Steven M. Mirin, Paul J. Orsulak
    Pages 137-150
  9. James Ellingboe, Steven M. Mirin, Roger E. Meyer, Jack H. Mendelson
    Pages 151-175
  10. Steven M. Mirin, Roger E. Meyer, James Ellingboe, Jack H. Mendelson
    Pages 177-198
  11. Joseph Albeck, Elizabeth Rider, Steven M. Mirin, Roger E. Meyer
    Pages 199-213
  12. Roger E. Meyer, Steven M. Mirin, Fred Zackon
    Pages 215-230
  13. Roger E. Meyer, Steven M. Mirin
    Pages 231-247
  14. Back Matter
    Pages 249-254

About this book

Introduction

The simple fact that the authors were able to give injectable heroin to volunteers for addictive self-administration at a Harvard facility may elude the notice it deserves. On the other hand, resec:irch questions center­ ing on whether heroin is linked to a craving for pleasure or relief of pain might raise the transplanted hackles of those who simplistically see scien­ tists as pursuing only transparent trivialities. In truth, this report is about a historical and pioneering step in clinical research on a major unsolved problem of the biological-social-psychological roots of addiction. The research questions posed are clearly relevant both to the design of effec­ tive treatments (and treatment policy) and to the basic science search that could help our understanding of how addictive drugs capture such power­ ful control over behavior. Heroin was synthesized and has been available, along with aspirin, for over three-quarters of a century. Yet with all the tools of Western sci­ ence, and with the enormous and growing social, personal, and economic costs of world-wide heroin use, we-surprisingly--

Keywords

Opiate behavior clinical research drugs hand pain psychopathology research treatment

Authors and affiliations

  • Roger E. Meyer
    • 1
  • Steven M. Mirin
    • 2
    • 3
  1. 1.University of Connecticut Medical SchoolFarmingtonUSA
  2. 2.Harvard Medical SchoolBelmontUSA
  3. 3.McLean HospitalBelmontUSA

Bibliographic information