Senescence

Dominant or Recessive in Somatic Cell Crosses?

  • Warren W. Nichols
  • Donald G. Murphy

Part of the Cellular Senescence and Somatic Cell Genetics book series (CSSCG, volume 2)

Table of contents

  1. Front Matter
    Pages i-x
  2. Thomas H. Norwood, Holger Hoehn, Andrew O. Martinez, George M. Martin
    Pages 23-38
  3. Rosalind Yanishevsky, Gretchen H. Stein
    Pages 73-79
  4. Orlando J. Miller
    Pages 105-109
  5. John W. Littlefield, Wai Nang Choy, Joshua Epstein
    Pages 111-120
  6. Back Matter
    Pages 121-123

About this book

Introduction

This monograph, Senescence; Dominant or Recessive In Somatic Cell Crosses? represents the second annual workshop to promote theory and concept development in aging research. These workshops are part of a resource to bank cultured cells of special interest to aging research that was established at the Institute for Medical Research in Camden. New Jersey. by the National Institute on Aging in 1974. The underlying theme of the workshops is the use of cultured cells in a variety of somatic cell genetic systems designed to define mechanisms of in vitra cellular scen­ escence and the possible insights that this may provide to the problems of in viva aging. The concept also includes bringing together workers from a variety of disciplines to stimulate new and innovative thoughts and work in the area. The current work­ shop focuses on the relative role of nucleus and cytoplasm on determining the in vitra lifespan of human diploid cells as well as the relative influence of old and young cells when combined within a single cell structure. The techniques and procedures discussed should make significant contributions to understanding in vitra senescence and may lead to the mapping of an area or areas of the genome linked to senescence as is being accomplished with viral transformation of normal cells. Warren W. Nichols Donald G. Murphy ~i Contents Theoretic Mechanisms of in vitpo Senescence 1 F. MaPott Sinex . . . . . . . . . . . . Senescence in Ce1l Cu1ture: An Accumu1ation of Errors or Terminal Differentiation? 13 Vincent J. GPistofaZo . . . . . . . . . . . . . .

Keywords

aging cell cells development genome lead research senescence

Editors and affiliations

  • Warren W. Nichols
    • 1
  • Donald G. Murphy
    • 2
  1. 1.Institute for Medical ResearchCamdenUSA
  2. 2.National Institute on AgingBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-2508-6
  • Copyright Information Springer-Verlag US 1977
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-2510-9
  • Online ISBN 978-1-4684-2508-6
  • About this book