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Low Density Lipoproteins

  • Charles E. Day
  • Robert S. Levy

Table of contents

  1. Front Matter
    Pages i-xx
  2. Isolation and Structure

  3. Metabolism

  4. Aberrations of Metabolism

    1. Front Matter
      Pages 149-149
    2. Waldo R. Fisher
      Pages 151-195
    3. Josef R. Patsch
      Pages 197-227
    4. Herbert J. Kayden
      Pages 271-278
  5. Comparative Biology

    1. Front Matter
      Pages 279-279
    2. G. D. Calvert
      Pages 281-319
  6. Relationship to Atherosclerosis

  7. Back Matter
    Pages 439-445

About this book

Introduction

Low density lipoproteins (LDL) are pathophysiologically important be­ cause of their central role in the disease atherosclerosis and because atherosclerosis is the leading cause of death in developed countries. Many researchers believe that a more detailed knowledge of the struc­ ture, function, and metabolism of LDL may eventually lead to a means to control atherosclerosis. For this reason a fairly large research effort has gone into the investigation of LDL over the past few years. The purpose of this book is to collect and summarize in one place most of the pub­ lished information on LDL through 1975. To this end more than 1500 references are cited in the papers that make up this volume. The A, B, C apolipoprotein classification system was adopted for use throughout this work. In addition to the A, B, C, and "D" families of apolipoproteins, apoE is used to designate the "arginine-rich" apolipo­ protein. This classification system is used because it is far less cumber­ some than other proposed classification schemes for apolipoproteins.

Keywords

Lipid amino acid biology enzymes information lead lipoprotein metabolism paper pharmacology polysaccharide protein proteins receptor synthesis

Editors and affiliations

  • Charles E. Day
    • 1
  • Robert S. Levy
    • 2
  1. 1.The Upjohn CompanyKalamazooUSA
  2. 2.Department of BiochemistryUniversity of Louisville School of MedicineLouisvilleUSA

Bibliographic information