Neurobiology of Cerebrospinal Fluid 1

  • James H. Wood

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Arthur M. Feldman, Mel H. Epstein, Saul W. Brusilow
    Pages 17-27
  3. Michael H. Ebert, Ronald Kartzinel, Rex W. Cowdry, Frederick K. Goodwin
    Pages 97-112
  4. Benjamin Rix Brooks, James H. Wood, Maria Diaz, Carol Czerwinski, Leon P. Georges, Jonas Sode et al.
    Pages 113-139
  5. Michael G. Ziegler, C. Raymond Lake, James H. Wood, Michael H. Ebert
    Pages 141-152
  6. Ian J. Butler, William E. Seifert, S. J. Enna
    Pages 153-160
  7. James H. Wood, Michael G. Ziegler, C. Raymond Lake, Ira Shoulson, Benjamin Rix Brooks
    Pages 161-169
  8. Theodore A. Hare, N. V. Bala Manyam, Bruce S. Glaeser
    Pages 171-187
  9. S. J. Enna, Michael G. Ziegler, C. Raymond Lake, James H. Wood, Benjamin Rix Brooks, Ian J. Butler
    Pages 189-196
  10. Paul F. Teychenne, C. Raymond Lake, Michael G. Ziegler
    Pages 197-206
  11. Bennett A. Shaywitz, Donald J. Cohen, Malcolm B. Bowers Jr.
    Pages 219-236

About this book


Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro­ spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var­ iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu­ lation and in elimination of possible sources of error.


biology brain neurobiology physiology

Editors and affiliations

  • James H. Wood
    • 1
    • 2
  1. 1.Division of NeurosurgeryUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.Pediatric Oncology BranchNational Cancer Institute National National Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1980
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-1041-9
  • Online ISBN 978-1-4684-1039-6
  • About this book