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Neurobiology of Cerebrospinal Fluid 1

  • James H. Wood

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Arthur M. Feldman, Mel H. Epstein, Saul W. Brusilow
    Pages 17-27
  3. Michael H. Ebert, Ronald Kartzinel, Rex W. Cowdry, Frederick K. Goodwin
    Pages 97-112
  4. Benjamin Rix Brooks, James H. Wood, Maria Diaz, Carol Czerwinski, Leon P. Georges, Jonas Sode et al.
    Pages 113-139
  5. Michael G. Ziegler, C. Raymond Lake, James H. Wood, Michael H. Ebert
    Pages 141-152
  6. Ian J. Butler, William E. Seifert, S. J. Enna
    Pages 153-160
  7. James H. Wood, Michael G. Ziegler, C. Raymond Lake, Ira Shoulson, Benjamin Rix Brooks
    Pages 161-169
  8. Theodore A. Hare, N. V. Bala Manyam, Bruce S. Glaeser
    Pages 171-187
  9. S. J. Enna, Michael G. Ziegler, C. Raymond Lake, James H. Wood, Benjamin Rix Brooks, Ian J. Butler
    Pages 189-196
  10. Paul F. Teychenne, C. Raymond Lake, Michael G. Ziegler
    Pages 197-206
  11. Bennett A. Shaywitz, Donald J. Cohen, Malcolm B. Bowers Jr.
    Pages 219-236
  12. John P. Laurent
    Pages 279-286
  13. Frederick A. Simeone, Phillip E. Vinall, John D. Pickard
    Pages 303-311
  14. Kunihiko Osaka, Hajime Handa, Shinichiro Okamoto
    Pages 313-323
  15. Alan S. Fleischer, George T. Tindall
    Pages 337-344
  16. A. Everette James Jr., Gary R. Novak, Ernst-Peter Strecker, Barry B. Burns, Francisco Correa-Paz, William J. Flor
    Pages 381-404
  17. Burton P. Drayer, Arthur E. Rosenbaum
    Pages 405-431
  18. John L. Trotter, Benjamin Rix Brooks
    Pages 465-486
  19. Steven R. Cohen, Benjamin Rix Brooks, Burk Jubelt, Robert M. Herndon, Guy M. McKhann
    Pages 487-494
  20. Jay D. Cook, Benjamin Rix Brooks
    Pages 507-523
  21. Edward A. Neuwelt, Suellen A. Hill
    Pages 525-547
  22. S. Clifford Schold, Dennis E. Bullard
    Pages 549-559
  23. David G. Poplack, Marc E. Horowitz, W. Archie Bleyer
    Pages 561-578
  24. Steven M. Reppert, David C. Klein, Mark J. Perlow
    Pages 579-589
  25. Kalmon D. Post, Bruce J. Biller, Ivor M. D. Jackson
    Pages 591-604
  26. Samuel P. Marynick, James H. Wood, D. Lynn Loriaux
    Pages 605-611
  27. Thomas G. Luerssen, Gary L. Robertson
    Pages 613-623
  28. Floyd E. Bloom, David S. Segal
    Pages 651-664
  29. Donald J. Cohen, Bennett A. Shaywitz, J. Gerald Young, Malcolm B. Bowers Jr.
    Pages 665-683
  30. Robert M. Post, James C. Ballenger, Frederick K. Goodwin
    Pages 685-717
  31. Daniël P. van Kammen, David E. Sternberg
    Pages 719-742
  32. David C. Jimerson, James H. Wood, Robert M. Post
    Pages 743-749

About this book

Introduction

Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro­ spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var­ iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu­ lation and in elimination of possible sources of error.

Keywords

biology brain neurobiology physiology

Editors and affiliations

  • James H. Wood
    • 1
    • 2
  1. 1.Division of NeurosurgeryUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.Pediatric Oncology BranchNational Cancer Institute National National Institutes of HealthBethesdaUSA

Bibliographic information