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Microbial genetics applied to biotechnology :

principles and techniques of gene transfer and manipulation

  • Book
  • © 1987

Overview

Authors:
  1. Venetia A. Saunders
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  2. Jon R. Saunders
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Table of contents (10 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introduction

    • Venetia A. Saunders, Jon R. Saunders
    Pages 1-2

  3. In Vivo Genetic Manipulation

    • Venetia A. Saunders, Jon R. Saunders
    Pages 3-53

  4. In Vitro Genetic Manipulation

    • Venetia A. Saunders, Jon R. Saunders
    Pages 54-162

  5. In Vivo and In Vitro Mutagenesis

    • Venetia A. Saunders, Jon R. Saunders
    Pages 163-218

  6. Optimisation of Expression of Cloned Genes

    • Venetia A. Saunders, Jon R. Saunders
    Pages 219-264

  7. Microbial Strain Improvement and Novel Products

    • Venetia A. Saunders, Jon R. Saunders
    Pages 265-305

  8. Medical and Veterinary Applications

    • Venetia A. Saunders, Jon R. Saunders
    Pages 306-332

  9. Plant Technology

    • Venetia A. Saunders, Jon R. Saunders
    Pages 333-383

  10. Environmental Biotechnology

    • Venetia A. Saunders, Jon R. Saunders
    Pages 384-406

  11. Conclusion

    • Venetia A. Saunders, Jon R. Saunders
    Pages 407-410

  12. Back Matter

    Pages 411-422
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Keywords

About this book

This book describes techniques of microbial genetics and how they may be applied to biotechnology. The text is concerned largely with the application of these techniques to microbial technology. We have therefore utilised illustrative material that is given in our own courses in applied micro­ biology. The book assumes in the reader a basic knowledge of microbial will prove useful to under­ genetics and industrial microbiology. We hope it graduates, postgraduates and others taking courses in applied micro­ biology. We would like to thank various colleagues, including John Carter, Julian Davies, Gordon Dougan, David Hopwood, Gwyn Humphreys, Alan McCarthy, David O'Connor, Tony Hart, Steve Oliver, Roger Pickup, Hilary Richards, Bob Rowlands, David Sherratt, Peter Strike, Richard Sykes and Liz Wellington, all of whom provided information at various stages during the writing of this book. Many thanks are also due to Linda Marsh for patiently typing the many drafts of the manuscript. 1 Introduction Natural genetic variation has always been exploited by man to improve the properties of microbial strains. Spontaneous mutations that arise in micro­ bial populations and that have properties advantageous to man have been gradually selected over centuries of use. However, it is only since the development of modem genetic techniques that more rational approaches have been possible. Such newer technologies have permitted the tailoring of microorganisms, plant or animal cells to manufacture specific products of commercial or social benefit and to manage the environment.

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