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Chemical Mutagens

Principles and Methods for Their Detection Volume 3

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  • ISBN: 978-1-4615-8972-3
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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xxii
  2. Specific-Locus Mutational Assay Systems for Mouse Lymphoma Cells

    • Donald Clive, W. Gary Flamm, James B. Patterson
    Pages 79-103
  3. Approaches to Monitoring Human Populations for Mutation Rates and Genetic Disease

    • J. V. Neel, T. O. Tiffany, N. G. Anderson
    Pages 105-150
  4. Repair of Chemical Damage to Human DNA

    • James D. Regan, R. B. Setlow
    Pages 151-170
  5. Tradescantia Stamen Hairs: A Radiobiological Test System Applicable to Chemical Mutagenesis

    • A. G. Underbrink, L. A. Schairer, A. H. Sparrow
    Pages 171-207
  6. Insect Chemosterilants as Mutagens

    • Alexej B. Bořkovec
    Pages 259-270
  7. The Literature of Chemical Mutagenesis

    • John S. Wassom
    Pages 271-287
  8. Back Matter

    Pages 289-304

About this book

The ready acceptance and wide demand for copies of the first two volumes of Chemical Mutagens: Principles and Methods Jar Their Detection have demon­ strated the need for wider dissemination of information on this timely and urgent subject. Therefore, it was imperative that a third volume be prepared to include more detailed discussions on techniques of some of the methods that were presented from a theoretical point of view in the first two volumes, and to update this rapidly expanding field with current findings and the new developments that have taken place in the past three years. Also included is a special chapter by Dr. Charlotte Auerbach giving the historical background of the discovery of chemical mutagenesis. Methods for recognizing mutagenic compounds in vitro are a necessary preliminary step toward arriving at satisfactory solutions for recognizing significant mutation rates in man, which must be done before our test­ tube methods of detection can be considered reliable. Two chapters in this volume make important contributions to this problem. Due to the increasing activity in efforts to perfect techniques for detecting chemical mutagens and their effects on man, it is planned to continue this series of volumes as necessary to keep abreast of current findings.

Keywords

  • DNA
  • Fixation
  • Handling
  • Mamma
  • Xeroderma pigmentosum
  • chromosome
  • development
  • genes
  • insects
  • molecule
  • mouse
  • mutagen
  • mutagenesis
  • mutation

Editors and Affiliations

  • Biology Division, Oak Ridge National Laboratory, Oak Ridge, USA

    Alexander Hollaender

  • University of Tennessee, Knoxville, USA

    Alexander Hollaender

Bibliographic Information

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • ISBN: 978-1-4615-8972-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 109.00
Price excludes VAT (USA)