The Fat-Soluble Vitamins

  • Hector F. DeLuca

Part of the Handbook of Lipid Research book series (HLRE, volume 2)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Luigi M. De Luca
    Pages 1-67
  3. H. F. DeLuca
    Pages 69-132
  4. Milton Leonard Scott
    Pages 133-210
  5. J. W. Suttie
    Pages 211-277
  6. Back Matter
    Pages 279-287

About this book

Introduction

The first demonstration of the existence of a vitamin and the full recognition of this fact are often attributed to the work of McCollum, who found that a sub­ stance in butterfat and cod-liver oil was necessary for growth and health of ani­ mals fed purified diets. It became obvious that an organic substance present in microconcentrations was vital to growth and reproduction of animals. Following the coining of the word vitamine by Funk, McCollum named this fat-soluble sub­ stance vitamin A. We can, therefore, state that vitamin A was certainly one of the first known vitamins, yet its function and the function of the other fat-soluble vitamins had remained largely unknown until recent years. However, there has been an explosion of investigation and new information in this field, which had remained quiescent for at least two or three decades. It is now obvious that the fat-soluble vitamins function quite differently from their water-soluble counter­ parts. We have learned that vitamin D functions by virtue of its being converted in the kidney to a hormone that functions to regulate calcium and phosphorus metabolism. This new endocrine system is in the process of being elucidated in detail, and in addition, the medical use of these hormonal forms of vitamin D in the treatment of a variety of metabolic bone diseases has excited the medical com­ munity.

Keywords

Calcium Vitamin D Vitamine chemistry kidney metabolism protein synthesis

Editors and affiliations

  • Hector F. DeLuca
    • 1
  1. 1.University of Wisconsin-MadisonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-8870-2
  • Copyright Information Springer-Verlag US 1978
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4615-8872-6
  • Online ISBN 978-1-4615-8870-2
  • About this book