Overview
- Editors:
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Robert C. King
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Department of Biological Sciences, Northwestern University, Evanston, USA
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Table of contents (18 chapters)
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The Molecular Organization of Chromosomes
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- Ru Chih C. Huang, Rex P. Hjelm Jr.
Pages 55-111
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Gene Transcripts
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Front Matter
Pages 187-187
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- Anton J. M. Berns, Hans Bloemendal
Pages 267-303
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Chloroplasts and Mitochondria
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Front Matter
Pages 369-369
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- Ruth Sager, Gladys Schlanger
Pages 371-423
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- Erhard Stutz, Arminio Boschetti
Pages 425-450
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- Thomas W. O’Brien, David E. Matthews
Pages 535-580
About this book
Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.
Editors and Affiliations
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Department of Biological Sciences, Northwestern University, Evanston, USA
Robert C. King
