Soft Tissue Sarcomas: Present Achievements and Future Prospects

  • J. Verweij
  • H. M. Pinedo
  • H. D. Suit

Part of the Cancer Treatment and Research book series (CTAR, volume 91)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Martin Harris, Ann L. Hartley
    Pages 1-8
  3. Jonathan A. Fletcher
    Pages 9-29
  4. Colin S. Cooper, Paul Cornes
    Pages 31-50
  5. Floro Miraldi, Lee P. Adler, Peter Faulhaber
    Pages 51-64
  6. Ugo Pastorino
    Pages 65-75
  7. Herman D. Suit, Ira J. Spiro, Matthew Spear
    Pages 95-105
  8. Phillip M. Devlin, Louis B. Harrison
    Pages 107-128
  9. Clive Harmer, Margaret Bidmead
    Pages 129-141
  10. William P. Steward
    Pages 157-172
  11. Jaap Verweij, Herbert M. Pinedo
    Pages 173-187
  12. A. M. M. Eggermont, H. Schraffordt Koops, J. M. Klausner, P. M. Schlag, B. B. R. Kroon, G. Ben-Ari et al.
    Pages 189-203
  13. Alberto S. Pappo, Charles B. Pratt
    Pages 205-222
  14. Back Matter
    Pages 223-232

About this book

Introduction

The previous volumes in this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, and this focus is continued in the present volume. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology tech­ niques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of patient prognosis as well as in providing data for planning the treatment strategy. The use of cytogenetics in this field is rapidly increasing and might enable the distinction of subgroups in specific histological tumor types. Furthermore, molecular biological studies not only help reveal inherited predispositions and details in tumor oncogenesis, but they may also provide additional predictive factors for tumor behavior. Further data on treatment strategy will be provided by diag­ nostic imaging, and in this volume the value of PET imaging, a relatively new achievement, is highlighted. As far as the actual treatment is concerned, surgery still provides the major opportunity for cure. The addition of radiotherapy to surgery is of utmost importance in efforts to spare as much tissue as possible. The chapters on the planning of radiotherapy, brachytherapy, and the treatment of benign soft tissue lesions using radiotherapy are new contributions to this book. One of the potential late problems of radiotherapy is the occurrence of secondary soft tissue sarcomas, which is discussed in Chapter 10.

Keywords

brachytherapy cytogenetics genetics histopathology imaging metastasis metastatic disease molecular genetics pathology radiotherapy tumor

Editors and affiliations

  • J. Verweij
    • 1
  • H. M. Pinedo
    • 2
  • H. D. Suit
    • 3
  1. 1.Department of Medical OncologyRotterdam Cancer InstituteRotterdamThe Netherlands
  2. 2.Department of Medical OncologyFree University HospitalAmsterdamThe Netherlands
  3. 3.Department of Radiation Medicine, Massachusetts General HospitalHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-6121-7
  • Copyright Information Kluwer Academic Publishers 1997
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7805-1
  • Online ISBN 978-1-4615-6121-7
  • Series Print ISSN 0927-3042
  • About this book