Analytical Use of Fluorescent Probes in Oncology

  • Elli Kohen
  • Joseph G. Hirschberg

Part of the NATO ASI Series book series (NSSA, volume 286)

Table of contents

  1. Front Matter
    Pages i-x
  2. Elli Kohen
    Pages 1-23
  3. Eva M. Sevick-Muraca, Christina L. Hutchinson, Tamara L. Troy
    Pages 31-40
  4. Enrico Gratton, Sergio Fantini, Maria Angela Franceschini, Scott Walker, John Maier
    Pages 41-52
  5. Philippe I. H. Bastiaens, Thomas M. Jovin
    Pages 53-57
  6. Roger M. Leblanc, Germain Puccetti
    Pages 59-64
  7. Joseph R. Lakowicz, Ewald Terpetschnig, Henryk Szmacinski, Henryk Malak, Józef Kuśba, Ignacy Gryczynski
    Pages 65-79
  8. R. R. Alfano, A. Katz
    Pages 81-89
  9. Marc Gèze, Jean-Michel Gaullier, Marc Bazin, René Santus
    Pages 113-121
  10. David G. Menter, Thomas W. Smith, Zhong Yun, John Patton, Larry V. McIntire, Garth L. Nicolson
    Pages 137-148
  11. Paolo Meda
    Pages 149-156
  12. Anne T. O’Meara, Bernd-Uwe Sevin, James Perras
    Pages 157-172
  13. Sylvie Cassanelli, Agnès Mialhe, Josette Louis, Daniel Seigneurin
    Pages 181-188
  14. S. Folli, P. Westermann, D. Braichotte, A. Pèlegrin, J. Mizeret, G. Wagnières et al.
    Pages 189-204

About this book

Introduction

Fluorescence is a very powerful tool for work at the frontier of cell biology, photobiology and bioinstrumentation. The stated aim of the workshop was to highlight the significance of fluorescence work for the understanding of cell and tissue physiology, physiopathology and pharmacology, particulary in terms of the analytical use of fluorescent probes in oncology. In the organization of the workshop a multidisciplinary approach was selected. The purpose of the Advanced Research Workshop (ARW) was to bring together researchers in the various disciplines of tissue optics, imaging, microspectrofluorometry and state of the art probes, in order to explore the full benefits that can be derived in biomedicine through the convergence of these approaches. When applied to in vivo and in situ studies, fluorescence and related optical methods enable us to explore within tissues, cells and organelles photon effects previously understood only in solution photochemistry. Processes which can be studied at the molecular level by photophysics, photochemistry and physical chemistry can be evaluated in living tissue by fluorescence spectroscopy and imaging at the intracellular level in terms of structure and function. Thus, fluorescence adds a new dimension to cell biology and physiology. This approach is now supported by a full and versatile, rapidly growing armamentarium of new selective probes for organelles, enzymes, cations, cytoskeleton and metabolic control.

Keywords

Organe Organelle apoptosis cyclin enzymes gene expression genes imaging metabolism microscopy physiology tissue

Editors and affiliations

  • Elli Kohen
    • 1
  • Joseph G. Hirschberg
    • 1
  1. 1.University of MiamiCoral GablesUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-5845-3
  • Copyright Information Springer Science+Business Media New York 1996
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7679-8
  • Online ISBN 978-1-4615-5845-3
  • About this book