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Apoptosis Genes

  • James W. Wilson
  • Catherine Booth
  • Christopher S. Potten

Table of contents

  1. Front Matter
    Pages i-ix
  2. J. W. Wilson, C. Booth, C. S. Potten
    Pages 1-4
  3. Maureen Murphy, Arnold J. Levine
    Pages 5-35
  4. Thomas Chittenden
    Pages 37-84
  5. Yue Eugene Chin, Xin-Yuan Fu
    Pages 119-142
  6. Andrew P. Gilmore, Charles H. Streuli
    Pages 143-165
  7. Asako Sugimoto, Masayuki Miura
    Pages 167-203
  8. John P. Wing, John R. Nambu
    Pages 205-241
  9. J. Marie Hardwick, Gary Ketner, Rollie J. Clem
    Pages 243-279
  10. Alastair Watson, Pedro Lowenstein
    Pages 281-303
  11. Back Matter
    Pages 305-310

About this book

Introduction

Apoptosis, or programmed cell death, is a natural process by which damaged or unwanted cells are dismantled in an orderly and atraumatic fashion. It is of critical importance in development, homeostasis, and cell population control. Research over the last decade is now enabling scientists to comprehend how genes and the protein products interact to control apoptosis. This has led to the current position where researchers may be able to directly modify the action of key proteins through gene therapy and antisense oligonucleotides.
Apoptosis Genes presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, Apoptosis Genes deals specifically with the regulation of apoptosis. Given the increased interest in the role of apoptosis genes in disease processes, this work will be useful to researchers investigating cancer, autoimmune disease, viral infection, cardiovascular disease, neurodegenerative disorders, AIDS, osteoporosis, and aging.

Keywords

Nucleotide aging apoptosis gene therapy genes proteins regulation signal transduction

Editors and affiliations

  • James W. Wilson
    • 1
  • Catherine Booth
    • 1
  • Christopher S. Potten
    • 1
  1. 1.Epithelial Biology Laboratory, CRC Section of Cell and Tumour BiologyPatterson Institute for Cancer ResearchManchesterUK

Bibliographic information