Direct Myocardial Revascularization: History, Methodology, Technology

  • Editors
  • Peter Whittaker
  • George S. Abela

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 211)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Bernard L. Tucker
    Pages 1-15
  3. John C. Tsang, Carlos M. Li, Ray C.-J. Chiu
    Pages 17-43
  4. Karin Przyklenk, Robert A. Kloner, Peter Whittaker
    Pages 61-80
  5. Takushi Kohmoto, Peter E. Fisher, Anguo Gu, Shu-ming Zhu, Carolyn DeRosa, Craig R. Smith et al.
    Pages 81-95
  6. Joel D. Eisenberg, On Topaz, George S. Abela
    Pages 97-119
  7. Peter Whittaker, Kalin Spariosu, Zonh-Zen Ho
    Pages 121-141
  8. John R. Crew
    Pages 143-154
  9. Daniel Burkhoff, Takushi Kohmoto, Carolyn DeRosa, Craig R. Smith
    Pages 155-162
  10. Heiko Schöder, Heinrich R. Schelbert
    Pages 163-178
  11. Charles A. Mack, Shailen R. Patel, Christopher J. Magovern, Ronald G. Crystal, Todd K. Rosengart
    Pages 179-200
  12. Back Matter
    Pages 201-202

About this book


The last five years have witnessed an increasing interest in the subject of transmyocardial laser revascularization (TMR) as illustrated by the number of abstracts presented at the meetings of the American Heart Association and the American College of Cardiology (Figure). The ideas and concepts associated with this particular method of myocardial revascularization have changed dramatically over even this short period of time. The original premise of "de-evolving" mammalian hearts to recreate a reptilian-like myocardial circulation by making multiple channels through the myocardium has been almost (but perhaps not quite) completely dismissed. Now, the most popular notion is that there is an angiogenic response to myocardial channel making. It is this development of new blood vessels that is thought to be responsible for the apparent improvements in symptoms and blood flow. Along the way, the idea that a channel could stay open and allow blood to flow directly from the ventricular chamber has found little support. Rather than directly explore all of these issues and merely duplicate previously published articles, our aim was to take a novel approach: that is, to step back from these arguments and provide perspective from the vantage point of distance. In the case of trans myocardial revascularization, distance comes both in terms of history and in terms of methodology and knowledge from other fields of research. Historically, innovative methods of myocardial revascularization are by no means uncommon. The first two chapters deal with this historical' perspective.


angiogenesis circulation coronary artery disease coronary heart disease physiology

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1999
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7305-6
  • Online ISBN 978-1-4615-5069-3
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site