Control of Gene Expression by Catecholamines and the Renin-Angiotensin System

  • Heinz Rupp
  • Bernard Maisch

Part of the Developments in Molecular and Cellular Biochemistry book series (DMCB, volume 33)

Table of contents

  1. Front Matter
    Pages i-v
  2. Catecholamine Influences on Gene Expression

    1. Front Matter
      Pages 3-3
    2. F. U. Müller, J. Neumann, W. Schmitz
      Pages 11-17
    3. Yoon S. Cho-Chung, Yun Gyu Park, Maria Nesterova, Youl Nam Lee, Yee Sook Cho
      Pages 29-34
    4. Andreas von Knethen, Bernhard Brüne
      Pages 35-43
    5. Ulrike Riese, Susanne Brenner, Wolf-Dietrich Döcke, Susanna Prösch, Petra Reinke, Michael Oppert et al.
      Pages 45-50
  3. Catecholamine and Angiotensin II Influences on Gene Expression

    1. Front Matter
      Pages 71-71
    2. John S. D. Chan, Tian-Tian Wang, Shao-Ling Zhang, Xing Chen, Serge Carrière
      Pages 73-79
    3. Subhash J. Vyas, Christopher M. Blaschak, Mala R. Chinoy, Edwin K. Jackson
      Pages 121-129
    4. Alexies Dagnino-Subiabre, Katerine Marcelain, Christian Arriagada, Irmgard Paris, Pablo Caviedes, Raul Caviedes et al.
      Pages 131-134
    5. Heinz Rupp, Martin Benkel, Bernhard Maisch
      Pages 135-142
  4. Angiotensin II Influences on Gene Expression

    1. Front Matter
      Pages 143-143
    2. Dagmara Mohuczy, M. Ian Phillips
      Pages 145-153
    3. Allan R. Brasier, M. Jamaluddin, Youqi Han, Cam Patterson, Marschall S. Runge
      Pages 155-169
    4. Eduardo Mascareno, M. A. Q. Siddiqui
      Pages 171-175
    5. Ryuichi Aikawa, Issei Komuro, Ryozo Nagai, Yoshio Yazaki
      Pages 177-182
    6. Levon M. Khachigian, Yoh Takuwa, Tucker Collins
      Pages 183-186
    7. Hiroaki Matsubara, Yasutaka Moriguchi, Yasukiyo Mori, Hiroya Masaki, Yoshiaki Tsutsumi, Yasunobu Shibasaki et al.
      Pages 187-201
    8. Kouichi Tamura, Yuqing E. Chen, Qin Chen, Nobuo Nyui, Masatsugu Horiuchi, Izumi Takasaki et al.
      Pages 203-209
    9. Satoshi Takeo, Yoshihisa Nasa, Kouichi Tanonaka, Fuminari Yamaguchi, Ken-ichi Yabe, Hideki Hayashi et al.
      Pages 227-235
  5. Back Matter
    Pages 237-242

About this book


The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression.
Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of many cells, the intriguing possibility arises that various disease are initiated or aggravated by such an imbalance. Catecholamine and angiotensin II influences can be in excess arising from, for example, hypercaloric food intake or psychosocial stress. During early progression of heart failure, sympathetic activity and angiotensin II influences also become increased. Due to beta-adrenergic receptor downregulation, depressed catecholamine influences are expected in the final stage of heart failure. An imbalanced influence of catecholamines and angiotensin II on gene expression leads to disordered molecular structures of the cell and an impaired cell function.
This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II. Basic biochemical processes are covered in detail and the potential of these pathways for explaining chronic diseases associated with excess catecholamine and angiotensin II influences should become apparent. It is hoped that this focussed issue triggers novel research into the development of drugs that are targeted at diseases characterized by an imbalanced gene expression involving catecholamines and angiotensin II.


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Editors and affiliations

  • Heinz Rupp
    • 1
  • Bernard Maisch
    • 2
  1. 1.Internal Medicine and Cardiology, Molecular Cardiology LaboratoryPhilipps University of MarburgMarburgGermany
  2. 2.Internal Medical, Molecular Cardiology LaboratoryPhilipps University of MarburgMarburgGermany

Bibliographic information