Neurobiology and Cell Physiology of Chemoreception

1. Front Matter

   Pages i-xii

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2. Morphology, Cyto-and Immunochemistry

   1. Front Matter

      Pages 1-1

      PDF

   2. Vascular Analysis of the Carotid Body in the Spontaneously Hypertensive Rat

      • J. A. Clarke, M. Burgh de Daly, H. W. Ead

      Pages 3-8

   3. Role of the Carotid Sinus Nerve and of Dopamine in the Biochemical Response of Sympathetic Tissues to Long-Term Hypoxia

      • Y. Dalmaz, J. M. Pequignot, J. M. Cottet-Emard, A. Vouillarmet, L. Peyrin

      Pages 9-15

   4. The Effects of Almitrine on (3H)5HT and (125I) Endothelin Binding to Central and Peripheral Receptors: An in Vitro Autoradiographic Study in the Cat

      • M. R. Dashwood, D. S. McQueen, R. M. Sykes, J. R. Muddle, M. B. de Daly, Y. Evrard et al.

      Pages 17-23

   5. Immunocytochemical and Neuro-Chemical Aspects of Sympathetic Ganglion Chemosensitivity

      • B. Dinger, Z.-Z. Wang, J. Chen, W.-J. Wang, G. Hanson, L. J. Stensaas et al.

      Pages 25-30

   6. Neuronal and Neuroendocrine Markers in the Human Carotid Body in Health and Disease

      • J.-O. Habeck, W. Kummer

      Pages 31-35

   7. The Effects of Chronic Hypoxaemia Upon the Structure of the Human Carotid Body

      • J.-O. Habeck, D. J. Pallot, A. Abramovici

      Pages 37-41

   8. Dopaminergic and Peptidergic Sensory Innervation of the Rat Carotid Body: Organization and Development

      • D. M. Katz, J. C. W. Finley, J. Polak

      Pages 43-49

   9. Effects of Cell-Free Perfusion and Almitrine Bismesylate on the Ultrastructure of Type-I Cell Mitochondria in the Cat Carotid Body

      • M. Kennedy, S. Giles, R. G. O’Regan, S. Feely, Y. Evrard

      Pages 51-59

   10. Multi-Unit Compartmentation of the Carotid Body Chemoreceptor by Perineurial Cell Sheaths: Immunohistochemistry and Freeze-Fracture Study

       • H. Kondo, M. Yamamoto

       Pages 61-66

   11. Light-and Electronmicroscopical Immunohistochemical Investigation of the Innervation of the Human Carotid Body

       • W. Kummer, J.-O Habeck

       Pages 67-71

   12. Serotonin (5-Hydroxytryptamine) Expression in Pulmonary Neuroendocrine Cells(NE) and a Netumor Cell Line

       • C. Newman, D. Wang, E. Cutz

       Pages 73-78

   13. Effects of Hypoxia on Cultured Chemoreceptors of the Rat Carotid Body: DNA Synthesis and Mitotic Activity in Glomus Cells

       • C. A. Nurse, C. Vollmer

       Pages 79-84

   14. Localization of Dopamine D2 Receptor mRNA in the Rabbit Carotid Body and Petrosal Ganglion by in situ Hybridization

       • A. Schamel, A. Verna

       Pages 85-91

   15. Noradrenergic Glomus Cells in the Carotid Body: An Autoradiographic and Immunocytochemical Study in the Rabbit and Rat

       • A. Verna, A. Schamel, J.-M. Pequignot

       Pages 93-100

3. Molecular Biology, Biophysics and Biochemistry

   1. Front Matter

      Pages 101-101

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   2. The Modulation of Intracellular pH in Carotid Body Glomus Cells by Extracellular pH and pCO2

      • K. J. Buckler, R. D. Vaughan-Jones, C. Peers, D. Lagadic-Gossmann, P. C. G. Nye

      Pages 103-109

   3. Evidence for Glucose Uptake in the Rabbit Carotid Body

      • M. A. Delpiano

      Pages 111-116

   4. Effects of Inorganic Calcium Channel Blockers on Carotid Chemosensory Responses in the Cat

      • C. Di Giulio, A. Mokashi, W.-X. Huang, L. Morelli, P. G. Data

      Pages 117-121

This volume records the papers presented in Chieti, Italy, at the 1991 meeting of the International Society for Arterial Chemoreception (ISAC). This was the eleventh of a series of assemblies held since 1959. This field of research, which examines the critical function and mechanisms of O and pHIPC0 sensitive cells in 2 2 the body, is unique in that it encompasses diverse biological and medical areas. The reader of this book will note chapters concerning modem techniques like in situ hybridization; analysis of cell membrane channels and intracellular ion movements; immunohistochemistry of peptides, hormones, and the corresponding receptors of chemoreceptor cells; and systemic analysis of reflex pathways involving chemoreceptor cells and their meaning in health and disease. This broad spectrum will appeal to readers interested in the chemoreceptor field, as well as young scientists seeking a scientific field where not only structural analysis but also a sense for functional connections is required. In recognition of the importance of the contribution of a new scientific generation to this field, ISAC awarded the prestigious F. de Castro-C. Heymans­ E. Neil prize to A. G6rlach, a young scientist. Also at this meeting, the Ferdinando Data Foundation Award, for helping scientists from non-developed countries to pursue their interest in chemoreception, was initiated. ISAC held plenary lectures in honor of C. Eyzaguirre and R. Forster, both of whom have contributed greatly to research in the chemoreceptor field.

• Peptide
• biology
• cell
• cell membrane
• cell physiology
• cells
• cognition
• membrane
• neurobiology
• physiology
• receptor

• Università degli Studi “G. D’Annunzio”, Chieti, Italy

  P. G. Data

• Max-Planck-Institut für Molekulare Physiologie, Dortmund, Germany

  H. Acker

• University of Pennsylvania, Philadelphia, USA

  S. Lahiri

Policies and ethics