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Epidemiological Aspects of Cutaneous Malignant Melanoma

  • Richard P. Gallagher
  • J. Mark Elwood

Part of the Developments in Oncology book series (DION, volume 73)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Recent Progress in Melanoma Research

    1. Front Matter
      Pages 1-1
    2. Richard P. Gallagher, J. Mark Elwood
      Pages 3-12
  3. Solar and Artificial Ultraviolet Radiation and Melanoma

  4. Nevi and Melanoma

    1. Front Matter
      Pages 129-129
    2. Leslie K. Dennis, Emily White
      Pages 131-149
    3. Julia A. Newton, Veronique Bataille
      Pages 151-158
    4. Elizabeth A. Holly, John W. Kelly, David K. Ahn, Steven N. Shpall, Judith I. Rosen
      Pages 159-172
  5. Occupation and Melanoma

    1. Front Matter
      Pages 173-173
    2. Margaret M. Hornstra, Mark J. Klan, Dan S. Sharp
      Pages 187-191
  6. Pregnancy and Hormonal Factors and Melanoma

    1. Front Matter
      Pages 207-207
    2. Elizabeth A. Holly, Rosemary D. Cress
      Pages 209-221
    3. Elizabeth A. Holly
      Pages 223-239
  7. Diet and Melanoma

    1. Front Matter
      Pages 241-241
    2. Constance S. Kirkpatrick
      Pages 243-251
    3. Loic Le Marchand, Jean H. Hankin, Laurence N. Kolonel, Lynne R. Wilkens
      Pages 253-261
  8. Prevention and Early Detection of Melanoma

    1. Front Matter
      Pages 263-263
    2. Marianne Berwick, Neil Dubin, George Roush, Raymond Barnhill
      Pages 265-271
    3. Howard K. Koh, Donald R. Miller, Alan C. Geller, Robert A. Lew
      Pages 289-303
  9. Future Directions in Melanoma Research

    1. Front Matter
      Pages 305-305
  10. Back Matter
    Pages 325-329

About this book

Introduction

Significant progress has been made in recent years in understanding the origins of cutaneous maligant melanoma. Knowledge of the relationship between solar radiation and melanoma has changed and it now appears that both the character and timing of exposure may be more important than total cumulative dose in accounting for risk. The melanoma-sunlight model may prove an instructive heuristic exercise for environmental epidemiology, as we currently tend to restrict ourselves to a search for uniform total dose--response relationships between cancers and suspected environmental carcinogens.
The study of the relationship between acquired melanocytic nevi and melanoma has led to useful new information about predictors of melanoma risk, and in addition has opened new perspectives on the development of nevi in children. Definition of the factors for nevus development in children may lead to the possibility of primary prevention programs for melanoma in younger generations of children.
Recent new evidence suggests that certain occupational groups may be at elevated risk of melanoma. A great deal of work is going into the study of ways of screening high risk populations in order to detect melanoma at its earliest stages when current treatment protocols are most effective. The visibility of lesions on the skin challenges classical definitions of early detection and screening in epidemiology.

Keywords

Cancer Cancer Screening Epidemiological Epidemiology Prevention Primary prevention screening

Editors and affiliations

  • Richard P. Gallagher
    • 1
  • J. Mark Elwood
    • 2
  1. 1.British Columbia Cancer AgencyVancouverCanada
  2. 2.University of OtagoDunedinNew Zealand

Bibliographic information