The Cell Cycle

Regulators, Targets, and Clinical Applications

  • Valerie W. Hu

Table of contents

  1. Front Matter
    Pages i-xi
  2. Regulators of the Cell Cycle

    1. Front Matter
      Pages 1-1
    2. Charles J. Sherr, Hitoshi Matsushime, Jun-ya Kato, Dawn E. Quelle, Martine F. Roussel
      Pages 17-23
    3. David L. Brautigan, Jian Chen, Fran Pinault, Jeremy Somers, Richard Zimmerman
      Pages 25-32
    4. Xiao-Wen Guo, John P. H. Th’ng, Richard A. Swank, E. Morton Bradbury
      Pages 41-49
    5. Luke Alphey, Helen White-Cooper, David Glover
      Pages 51-57
  3. Control of Cell Proliferation

    1. Front Matter
      Pages 59-59
    2. David J. Robbins, Erzhen Zhen, Mangeng Cheng, Colleen A. Vanderbilt, Douglas Ebert, Clark Garcia et al.
      Pages 61-66
    3. J. Carl Barrett, Cynthia A. Afshari
      Pages 79-89
    4. Joseph R. Nevins
      Pages 91-97
    5. Elias Coutavas, Mindong Ren, Joel D. Oppenheim, Vijay Yajnik, Peter D’Eustachio, Mark G. Rush
      Pages 99-110
  4. Cell Cycle Control of Gene Expression and Repair

    1. Front Matter
      Pages 121-121
    2. Franca LaBella, Rosanna Martinelli, Neil Segil, Nathaniel Heintz
      Pages 123-125
    3. Gregory S. Naeve, Li-jing Li, Lin Guo, Ajay Sharma, Amy S. Lee
      Pages 127-139
    4. Jill E. Slansky, Peggy J. Farnham
      Pages 149-154

About this book


Interest in the cell cycle has grown explosively in recent years as a result of the identification of key cell cycle regulators and their substrates. Aside from enhancing our understanding of normal cellular growth controls, this new knowledge has also becn valuable in elucidating mechanisms of growth deregulation which occur in diseased states, such as cancer and, in some instances, viral or parasitic infections. The Thirteenth Washington International Spring Symposium was organized with the intention of bringing together scientists working on different aspects of the cell cycle. Scientific topics presented ranged from molecular regulators and effectors to mitosis­ specific changes in cell architecture to the role of the cell cycle in development and disease. The goal of this gathering was to help formulate a more comprehensive and integrated picture of events driving and being driven by the cell cycle, as well as to evaluate the possibilities for clinical application of this knowledge. This symposium, held in Washington, D.C. from May 10-14, 1993, was attended by more than 400 scientists from 20 countries, including many of the scientific leaders in this field. This volume contains most of the papers presented at the seven plenary sessions in addition to selected contributions from a total of nine special oral and poster sessions.


cellular growth cyclin development gene expression regulation transcription

Editors and affiliations

  • Valerie W. Hu
    • 1
  1. 1.The George Washington University Medical CenterUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6027-8
  • Online ISBN 978-1-4615-2421-2
  • About this book