Endocrinology of Embryo-Endometrium Interactions

  • Stanley R. Glasser
  • Joy Mulholland
  • Alexandre Psychoyos

Part of the Reproductive Biology book series (RBIO)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Endocrinology of Embryo-Endometrial Interactions: A Hundred Years of Fascinating Discoveries

  3. Contributions of Comparative Studies to Understanding Mechanisms of Implantation

  4. Uterine Receptivity: Experimental Studies

  5. Uterine Receptivity: Clinical Studies

    1. J. Mandelbaum, M. Plachot, A. M. Junca, J. Cohen, J. Salat-Baroux
      Pages 93-105
    2. Peter C. Svalander, Paul V. Holmes, Kristina Gemzell-Danielsson, Marja-Liisa Swahn, Matts Wikland, Marc Bygdeman
      Pages 125-135
  6. The M.C. Chang Memorial Lecture

  7. Pregnancy Recognition

    1. Takahide Mori, Hideharu Kanzaki
      Pages 163-165
    2. K. Imakawa, S. D. Helmer, L. A. Harbison, C. S. R. Meka, R. K. Christenson
      Pages 167-181
    3. Jacques Martal, Nasser-Eddine Assal, Aines Assal, Kamel Zouari, Louis Huynh, Nicole Chêne et al.
      Pages 195-216
  8. Endometrial Responses To Receptivity

About this book

Introduction

Early embryonic loss is a continuing social and economic global problem. In human populations the estimates of interruptions early in pregnancy range from 35-60%. In animal husbandry (swine, ruminants) fully 30% of pregnancies fail to survive early events of gestation. The futility associated with this persistant high risk is even more unsettling because of advances made in assisted reproductive technology which, although this very selective methodology has added to our knowledge of embryo-endometrial interactions, has resulted in a birth rate of only 14%. These studies have instigated comparisons of the live relative contributions of the embryo and the uterus to the outcome of pregnancy. These analyses have shown that we have learned significantly less about the role of the uterus in deciding the outcome of either natural or assisted pregnancies. In 1979 a quotation by George Corner was used to set the tone of a meeting that was devoted to discussion of the cellular and molecular aspects of implantation. In spite of the proliferation in research activity which occurred in the following 15 years our real understanding of the embryo transfer process has fallen short of our expectations. We use the Corner quotation, once again, to preface this symposium so that we may recall that the fundamental nature of the process which regulates embryo-endometrial interactions still escapes us.

Keywords

Endometrium G proteins Insulin Uterus biology birth embryo endocrinology genes growth hormone hormones interaction pregnancy protein

Editors and affiliations

  • Stanley R. Glasser
    • 1
  • Joy Mulholland
    • 1
  • Alexandre Psychoyos
    • 2
  1. 1.Baylor College of MedicineHoustonUSA
  2. 2.Hôpital Bicêtre, Bâtiment INSERM Gregory PincusBicêtreFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-1881-5
  • Copyright Information Plenum Press, New York 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5766-7
  • Online ISBN 978-1-4615-1881-5
  • About this book