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Aspartic Proteinases

Structure, Function, Biology, and Biomedical Implications

  • Kenji Takahashi

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 362)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Gastric Aspartic Proteinases: Plenary Lectures

    1. Ben M. Dunn, Paula E. Scarborough, W. Todd Lowther, Chetana Rao-Naik
      Pages 1-9
    2. Nadezhda Tarasova, Michael James, Stanley Moore, Anita Sielecki, Maia Chernaia
      Pages 11-18
    3. Bent Foltmann, Kenneth Harlow, Gunnar Houen, Peter K. Nielsen, Per Sangild
      Pages 41-51
    4. Kenji Takahashi, Masao Tanji, Etsuko Yakabe, Akira Hirasawa, Senerath B. P. Athauda, Takashi Kageyama
      Pages 53-65
    5. G. Pals, P. H. S. Meijerink, J. Defize, J. P. Bebelman, M. Strunk, F. Arwert et al.
      Pages 67-75
  3. Gastric Aspartic Proteinases: Poster Reports

    1. Nadezhda Tarasova, Nancy D. Denslow, Benny F. Parten, Nha Tran, Hung P. Nhuyen, Arwyn Jones et al.
      Pages 77-81
    2. Raj R. V. Dhanaraj, Jim E. Pitts, Phil Nugent, Poonsook Orprayoon, Jon B. Cooper, Tom L. Blundell et al.
      Pages 95-99
    3. Pal Bela Szecsi, Hans Lilja
      Pages 101-105
    4. Masao Ichinose, Shinko Tsukada, Kazumasa Miki, Nobuyuki Kakei, Masashi Matsushima, Naohisa Yahagi et al.
      Pages 107-113
    5. Nobuyuki Kakei, Masao Ichinose, Shinko Tsukada, Masae Tatematsu, Noriaki Tezuka, Naohisa Yahagi et al.
      Pages 115-123
    6. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Masahiro Kido et al.
      Pages 131-137
    7. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Takehisa Suzuki et al.
      Pages 139-143
    8. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Masahiro Kido et al.
      Pages 145-148
    9. Masashi Matsushima, Tomonori Wada, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi et al.
      Pages 149-154
  4. Non-Gastric Aspartic Proteinases: Plenary Lectures

    1. C. F. Aguilar, V. Dhanaraj, K. Guruprasad, C. Dealwis, M. Badasso, J. B. Cooper et al.
      Pages 155-166
    2. Dennis J. Hoover, Bruce A. Lefker, Robert L. Rosati, Ronald T. Wester, Edward F. Kleinman, Jasjit S. Bindra et al.
      Pages 167-180
    3. John W. Erickson, Eric T. Baldwin, T. Narayana Bhat, Sergei Gulnik
      Pages 181-192
    4. Peter Metcalf, Martin Fusek
      Pages 193-200
    5. Senarath B. P. Athauda, Takashi Kageyama, Takayuki Takahashi, Hideshi Inoue, Masao Ichinose, Masanori Ukai et al.
      Pages 201-210
    6. Takashi Kageyama, Masao Ichinose, Kazumasa Miki, Akihiko Moriyama, Satoshi Yonezawa, Masao Tanji et al.
      Pages 211-221
    7. R. Michael Roberts, Sancai Xie, Robert J. Nagel, Bonn Low, Jonathan Green, Jean-François Beckers
      Pages 231-240
    8. Jukka Kervinen, Kirsi Törmäkangas, Pia Runeberg-Roos, Kunchur Guruprasad, Tom Blundell, Teemu H. Teeri
      Pages 241-254
  5. Non-Gastric Aspartic Proteinases: Poster Reports

    1. T. Inagami, K. Murakami, F. Suzuki, N. Tanaka, K. Takeuchi, Y. Muramoto et al.
      Pages 267-272
    2. Gerald Koelsch, Peter Metcalf, Vaclav Vetvicka, Martin Fusek
      Pages 273-278
    3. Lotte Bach Larsen, Torben Ellebæk Petersen
      Pages 279-283
    4. Borut Štrukelj, Maja Ravnikar, Pika Meško, Mateja Poljšak-Prijatelj, Joše Pungerčar, Gregor Kopitar et al.
      Pages 293-298
    5. Senarath B. P. Athauda, Hideo Arakawa, Takayuki Takahashi, Masaaki Nishigai, Eiji Ido, Hiroyuki Kyushiki et al.
      Pages 305-313
    6. Jeffrey Hill, Douglas Montgomery, John Kay
      Pages 315-318
    7. Masayuki Yamada, Takao Matsuba, Takeshi Azuma, Hideo Suzuki, Kenji Yamamoto, Hitoshi Hori
      Pages 319-324
    8. Hiroshi Iida, Takao Matsuba, Masayuki Yamada, Takeshi Azuma, Hideo Suzuki, Kenji Yamamoto et al.
      Pages 325-330
    9. Takayuki Tsukuba, Yamada Masayuki, Hitoshi Hori, Takeshi Azuma, Kenji Yamamoto
      Pages 331-334
    10. Motoyuki Yajima, Kazuyoshi Tominaga, Hiroshi Nakanishi, Kenji Yamamoto
      Pages 341-343
    11. Satoshi Yonezawa, Masao Ichinose, Shinko Tsukada, Kazumasa Miki, Takashi Kageyama
      Pages 345-348
    12. Shinko Tsukada, Masao Ichinose, Kazumasa Miki, Nobuyuki Kakei, Masashi Matsushima, Naohisa Yahagi et al.
      Pages 349-355
    13. Hiroshi Fukamachi, Masao Ichinose, Satoshi Ishihama, Shinko Tsukada, Chie Furihata, Satoshi Yonezawa et al.
      Pages 357-361
    14. Takeshi Azuma, Masayuki Yamada, Hajime Murakita, Yasuyuki Nishikawa, Yoshihiro Kohli, Kenji Yamamoto et al.
      Pages 363-366
    15. Carlos Faro, Paula Veríssimo, Yingzhang Lin, Jordan Tang, Euclides Pires
      Pages 373-377

About this book

Introduction

The 5th International Conference on Aspartic Proteinases was held on September 19 through 24, 1993, at Naito Museum of Pharmaceutical Science and Industry, Kawashima­ cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present and discuss new information on the structure, function, and biology, and related topics, including biomedical implications, of aspartic proteinases, and this book is a collec­ tion of nearly all the papers presented at the meeting. Aspartic proteinases belong to one of the four major classes of proteinases, the others being serine, cysteine, and metalloproteinases, and are so called since they have two catalytic aspartic acid residues in common in their active sites. Most of them are optimally active at acidic pH, hence the long-used name "acid proteinases," which, indeed, was the major title of the first conference of this series. However, some of them are active at around neutral pH, indicating their physiological roles in a wider range of pH than hitherto considered.

Keywords

Amino acid Embryo Nucleotide Termination biosynthesis gene expression genes proteins saccharomyces cerevisiae transcription

Editors and affiliations

  • Kenji Takahashi
    • 1
  1. 1.The University of TokyoTokyoJapan

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-1871-6
  • Copyright Information Plenum Press, New York 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5761-2
  • Online ISBN 978-1-4615-1871-6
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site