Aspartic Proteinases

Structure, Function, Biology, and Biomedical Implications

  • Kenji Takahashi

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 362)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Gastric Aspartic Proteinases: Plenary Lectures

    1. Ben M. Dunn, Paula E. Scarborough, W. Todd Lowther, Chetana Rao-Naik
      Pages 1-9
    2. Nadezhda Tarasova, Michael James, Stanley Moore, Anita Sielecki, Maia Chernaia
      Pages 11-18
    3. Bent Foltmann, Kenneth Harlow, Gunnar Houen, Peter K. Nielsen, Per Sangild
      Pages 41-51
    4. Kenji Takahashi, Masao Tanji, Etsuko Yakabe, Akira Hirasawa, Senerath B. P. Athauda, Takashi Kageyama
      Pages 53-65
    5. G. Pals, P. H. S. Meijerink, J. Defize, J. P. Bebelman, M. Strunk, F. Arwert et al.
      Pages 67-75
  3. Gastric Aspartic Proteinases: Poster Reports

    1. Nadezhda Tarasova, Nancy D. Denslow, Benny F. Parten, Nha Tran, Hung P. Nhuyen, Arwyn Jones et al.
      Pages 77-81
    2. Raj R. V. Dhanaraj, Jim E. Pitts, Phil Nugent, Poonsook Orprayoon, Jon B. Cooper, Tom L. Blundell et al.
      Pages 95-99
    3. Pal Bela Szecsi, Hans Lilja
      Pages 101-105
    4. Masao Ichinose, Shinko Tsukada, Kazumasa Miki, Nobuyuki Kakei, Masashi Matsushima, Naohisa Yahagi et al.
      Pages 107-113
    5. Nobuyuki Kakei, Masao Ichinose, Shinko Tsukada, Masae Tatematsu, Noriaki Tezuka, Naohisa Yahagi et al.
      Pages 115-123
    6. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Masahiro Kido et al.
      Pages 131-137
    7. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Takehisa Suzuki et al.
      Pages 139-143
    8. Masashi Matsushima, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi, Masahiro Kido et al.
      Pages 145-148
    9. Masashi Matsushima, Tomonori Wada, Kazumasa Miki, Masao Ichinose, Nobuyuki Kakei, Naohisa Yahagi et al.
      Pages 149-154

About this book


The 5th International Conference on Aspartic Proteinases was held on September 19 through 24, 1993, at Naito Museum of Pharmaceutical Science and Industry, Kawashima­ cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present and discuss new information on the structure, function, and biology, and related topics, including biomedical implications, of aspartic proteinases, and this book is a collec­ tion of nearly all the papers presented at the meeting. Aspartic proteinases belong to one of the four major classes of proteinases, the others being serine, cysteine, and metalloproteinases, and are so called since they have two catalytic aspartic acid residues in common in their active sites. Most of them are optimally active at acidic pH, hence the long-used name "acid proteinases," which, indeed, was the major title of the first conference of this series. However, some of them are active at around neutral pH, indicating their physiological roles in a wider range of pH than hitherto considered.


Amino acid Embryo Nucleotide Termination biosynthesis gene expression genes proteins saccharomyces cerevisiae transcription

Editors and affiliations

  • Kenji Takahashi
    • 1
  1. 1.The University of TokyoTokyoJapan

Bibliographic information

  • DOI
  • Copyright Information Plenum Press, New York 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5761-2
  • Online ISBN 978-1-4615-1871-6
  • Series Print ISSN 0065-2598
  • About this book