Cardiovascular Physiology in the Genetically Engineered Mouse

  • Brian D. Hoit
  • Richard A. Walsh

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 238)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Part One

    1. Albrecht G. Schmidt, Vivek J. Kadambi, Karen B. Young, Evangelia G. Kranias
      Pages 17-38
    2. Tetsuo Minamino, Michael D. Schneider
      Pages 39-52
    3. Susan Acton, Raju Jeyaseelan, Vivek J. Kadambi, Roger E. Breitbart
      Pages 53-61
    4. Steven A. Fisher
      Pages 63-69
  3. Part Two

    1. Zhi Su, William H. Barry
      Pages 71-89
    2. Nipavan Chiamvimonvat, M. Jane Lalli, Atsuko Yatani
      Pages 91-112
    3. Joanne S. Ingwall, Maryam M. Javadpour, Wenfeng Miao
      Pages 151-163
    4. Brian D. Hoit
      Pages 191-205
    5. Dimitrios Georgakopoulos, David A. Kass
      Pages 207-222
    6. Michael R. Zile, Anne Hauet, Elizabeth Hapke, Janet Simsic
      Pages 223-236
    7. Charles I. Berul, Paul J. Wang
      Pages 237-256
    8. Stephen F. Vatner, Gen Takagi, Kuniya Asai, Richard P. Shannon
      Pages 257-275
    9. Kavin H. Desai, Daniel Bernstein
      Pages 277-302
  4. Part Three

    1. Roy L. Sutliff, Richard J. Paul
      Pages 319-334
    2. Yasuhiro Ikeda, John Ross Jr.
      Pages 335-352
    3. Kimimasa Tobita, Joseph P. Tinney, Bradley B. Keller
      Pages 353-376
    4. Roee S. Lazebnik, David L. Wilson
      Pages 377-396
  5. Back Matter
    Pages 397-403

About this book


The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice. It is the primary objective of this second edition to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for the investigator interested in the functional methods used to characterize the murine cardiovascular phenotype. However, this guidebook is a more comprehensive text than its predecessor; although the major objectives enumerated in the first edition have not substantially changed, they have been refined in keeping with the increased sophistication of the molecular biologist, geneticist, and physiologist in each other's discipline. Each chapter has been expanded and updated, richly enhanced with original tables and figures, and in many cases, extensively rewritten. Eight chapters written by internationally recognized experts have been added; this represents a 43 % increase from the first edition.


cardiovascular cardiovascular function genetics microscopy molecular biology physiology recombination ultrasound

Editors and affiliations

  • Brian D. Hoit
    • 1
  • Richard A. Walsh
    • 1
  1. 1.Case Western Reserve University and University Hospitals of ClevelandUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5661-5
  • Online ISBN 978-1-4615-1653-8
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site