Molecular Biology and Physiology of Water and Solute Transport

  • Stefan Hohmann
  • Søren Nielsen

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Structure Function Analysis of Aquaporins and Glycerol Facilitators

    1. Front Matter
      Pages 1-1
    2. Roslyn M. Bill, Kristina Hedfalk, Sara Karlgren, Jan Rydström, Stefan Hohmann
      Pages 3-11
    3. Thomas Braun, Ansgar Philippsen, Sabine Wirtz, Mario J. Borgnia, Peter Agre, Werner Kühlbrandt et al.
      Pages 13-21
    4. Laurence Duchesne, Isabelle Pellerin, Valérie Lagrée, Alexandrine Froger, Christian Delamarche, Jean-Pierre Le Caer et al.
      Pages 23-28
    5. Sapar M. Saparov, Ulrich Rothe, Mario J. Borgnia, Peter Agre, Peter Pohl
      Pages 41-48
    6. Isaiah Turnbull, Yun Lu, Alan S. Verkman, William R. Skach
      Pages 49-55
  3. Function, Physiological Roles and Regulation of Mamalian Aquaporins

    1. Front Matter
      Pages 57-57
    2. Eric Beitz, Hidetaka Kumagami, J. Peter Ruppersberg, Joachim E. Schultz, Peter Agre
      Pages 59-62
    3. Sophie Combet, Nancy Geffroy, Laurent Teillet, Véronique Berthonaud, Renée Gobin, Alexis Beckmann et al.
      Pages 63-68
    4. Olivier Devuyst, Sophie Combet, Jean-Luc Balligand, Eric Goffin, Jean-Marc Verbavatz
      Pages 69-75
    5. Carolyn A. Ecelbarger, Takashi Murase, Søren Nielsen, Ying Tian, Chung-Lin Chou, Beatriz Olson et al.
      Pages 77-83
    6. Marie-Louise Elkjær, Lene N. Nejsum, Uffe B. Jensen, Tae-Hwan Kwon, Jørgen Frøkiær, Søren Nielsen
      Pages 85-89
    7. Henrik Hager, Tae-Hwan Kwon, Mark Knepper, Jørgen Frøkiær, Søren Nielsen
      Pages 91-96
    8. Jin Suk Han, Un Sil Jeon, Kwon Wook Joo, Ho Joon Chin, Woosung Huh, Jung Sang Lee et al.
      Pages 97-105
    9. Zhiqiang Han, Rajkumar V. Patil
      Pages 107-113
    10. Warren G. Hill, John C. Mathai, Mark L. Zeidel
      Pages 115-122
    11. Kenichi Ishibashi, Michio Kuwahara, Yukio Kageyama, Sei Sasaki, Makoto Suzuki, Masashi Imai
      Pages 123-126

About this book


Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous.
In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport" to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.


Lipid Mammalia escherichia coli phenotype physiology plasma membrane proteins regulation tissue

Editors and affiliations

  • Stefan Hohmann
    • 1
  • Søren Nielsen
    • 2
  1. 1.Göteborg UniversityGöteborgSweden
  2. 2.Institute of AnatomyUniversity of ÅrhusÅrhusDenmark

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic / Plenum Publishers, New York 2000
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5439-0
  • Online ISBN 978-1-4615-1203-5
  • About this book