Implantable Defibrillator Therapy: A Clinical Guide

  • Antonio Pacifico
  • Gust H. Bardy
  • Martin Borggrefe
  • Philip D. Henry
  • Francis E. Marchlinski
  • Andrea Natale
  • Bruce I. Wilkoff

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 244)

Table of contents

  1. Front Matter
    Pages i-x
  2. Dirk Böcker, Martin Borggrefe
    Pages 1-14
  3. Philip D. Henry, Mike Hardage
    Pages 15-41
  4. Philip D. Henry, Antonio Pacifico
    Pages 43-62
  5. Philip D. Henry, Antonio Pacifico
    Pages 63-76
  6. Antonio Pacifico, Philip D. Henry
    Pages 77-112
  7. Adam H. Zivin, Gust H. Bardy
    Pages 113-137
  8. Adam Zivin, Gust H. Bardy
    Pages 139-145
  9. Antonio Pacifico, Philip D. Henry
    Pages 147-159
  10. Andrea M. Russo, Francis E. Marchlinski
    Pages 161-243
  11. Philip D. Henry, Antonio Pacifico
    Pages 245-257
  12. Stephen Pavia, Walid Saliba, Bruce L. Wilkoff
    Pages 259-278
  13. Stephen Pavia, Sergio L. Pinski, Andrea Natale
    Pages 279-323
  14. Mike Hardage, Philip D. Henry
    Pages 325-350
  15. Philip D. Henry, Antonio Pacifico
    Pages 351-394
  16. Antonio Pacifico, Gust H. Bardy, Martin Borggrefe, Philip D. Henry, Francis E. Marchlinski, Andrea Natale et al.
    Pages 395-397
  17. Back Matter
    Pages 399-410

About this book


Implantable defibrillators as originally conceived by Michel Mirowski were limited to the detection and automatic termination of ventricular fibrillation. In the original "AID" device, the detection algoritlun sought to distinguish sinus rhytlun from ventricular fibrillation by identifying the "more sinusoidal waveform of ventricular fibrillation. " The therapeutic intervention was elicited only once deadly polymorphic rhythms had developed. It was rapidly learned, however, that ventricular fibrillation is usually preceded by ventricular tachycardia. Mirowski recognized the pivotal importance of developing algoritllms based on heart rate. Ventricular tachycardia detection allowed the successful development of interventions for the termination of ventricular tachyarrhythmias before they degenerated into ventricular fibrillation. Current device therapy no longer confines itself to tlle termination of chaotic rhythms but seeks to prevent them. Diagnostic algorithms moved upward along the chain of events leading to catastrophic rhytlulls. Rate smoothing algorithms were developed to prevent postextrasystolic pauses from triggering ventricular and atrial tachyarrhytlmlias. Beyond the renaissance of ectopy-centered strategies, long-term prevention received increasing attention. Multisite pacing therapies provided by "Arrhythmia Management Devices" were designed to reduce the "arrhytlunia burden" and optimize the synergy of cardiac contraction and relaxation. Clinical evidence now suggests that atrial fibrillation prevention by pacing is feasible and tllat biventricular pacing may be of benefit in selected patients with heart failure. However, these applications of device therapy that generally require ventricular defibrillation backup remain investigational and were not considered in this book.


ICD arrhythmia complication complications depression diagnosis drug electrophysiology implant implantat implantation instrumentation physiology therapy training

Editors and affiliations

  • Antonio Pacifico
    • 1
  • Gust H. Bardy
    • 2
  • Martin Borggrefe
    • 3
  • Philip D. Henry
    • 1
  • Francis E. Marchlinski
    • 4
  • Andrea Natale
    • 5
  • Bruce I. Wilkoff
    • 6
  1. 1.Baylor College of Medicine and Texas Arrhythmia InstituteHoustonUSA
  2. 2.University of WashingtonSeattleUSA
  3. 3.Westfälische UniversitätMünsterGermany
  4. 4.Allegheny University HospitalsPhiladelphiaUSA
  5. 5.The Cleveland Clinic FoundationClevelandUSA
  6. 6.The Cleveland Clinic FoundationClevelandUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5372-0
  • Online ISBN 978-1-4615-1055-0
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site