Behavior Genetics of Psychopathology

1. Front Matter

   Pages i-viii

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2. Attention Deficit Hyperactivity Disorder: Insight from Quantitative Genetic Research

   • Alexis C. Frazier-Wood, Anna S. Rommel, Jonna Kuntsi

   Pages 1-32

3. Progress in Understanding the Causes of Autism Spectrum Disorders and Autistic Traits: Twin Studies from 1977 to the Present Day

   • Angelica Ronald, Rosa Hoekstra

   Pages 33-65

4. Genetic Influences on Depression and Anxiety in Childhood and Adolescence

   • Frances Rice

   Pages 67-97

5. Additional Evidence for Meaningful Etiological Distinctions Within the Broader Construct of Antisocial Behavior

   • S. Alexandra Burt

   Pages 99-119

6. Sleep and Psychopathology: Quantitative and Molecular Genetic Research on Comorbidity

   • Nicola L. Barclay, Alice M. Gregory

   Pages 121-152

7. Schizophrenia and Bipolar Disorder

   • Alastair G. Cardno, Edward Pepper

   Pages 153-183

8. Genetics of Substance Use Disorders

   • Arpana Agrawal, Michael T. Lynskey

   Pages 185-230

9. Behavioral Genetic Approaches to Understand the Etiology of Comorbidity

   • Erik G. Willcutt

   Pages 231-252

10. Gene–Environment Interactions (G×E) in Behavioral Genetics

    • Laramie Duncan

    Pages 253-281

11. Epigenetics of Psychopathology

    • Alicia K. Smith, Sasha E. Parets, Andrew W. Kim

    Pages 283-309

12. Future Directions in Genetics of Psychiatric Disorders

    • Naomi R. Wray, Enda M. Byrne, Sven Stringer, Bryan J. Mowry

    Pages 311-337

13. Back Matter

    Pages 339-344

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As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and medical domains. The discoveries surrounding the human genome and the advancement in molecular genetic technologies have  led to studies becoming increasingly sophisticated and yielding  yet more conclusive and useful results. This is certainly the case in the area of child and adult psychopathology.

 

Behavior Genetics of Psychopathology summarizes the state of the field, examining

the role of genes and environment as they affect common neurodevelopmental and psychiatric conditions. Emphasizing key research areas (comorbidities, twin studies, the integration of methods), the book assesses the current literature, offers up-to-date findings, sorts through lingering controversies, and identifies a clear future agenda for the field. Expertly-written chapters focus on issues of both general salience that shape behavior genetics of psychopathology, to specific disorders of major clinical importance, among them:

 

• ADHD: the view from quantitative genetic research.
• Autism spectrum disorders and their complex heterogeneity
• Genetic influences on anxiety and depression in childhood and adolescence.
• Evidence for etiologically-defined subgroups within the construct of antisocial behavior.
• Sleep and psychopathology: the reasons for their co-occurrence.
• Behavioral genetic approaches to the etiology of comorbidity.
• Epigenetics of psychopathology.

 

This combination of timeliness and depth of coverage make Behavior Genetics of Psychopathology a frontline resource for behavior geneticists, psychologists, psychiatrists, and neuroscientists, and is perfectly suited to graduate students looking to join these fields.

• comorbidity in psychopathology
• conduct order and antisocial behavior
• development of psychopathology
• gene-environment interaction
• genetics of psychiatric disorders
• genetics of psychosis

• Department of Psychology and NeuroScience, University of Colorado, Boulder, USA

  Soo Hyun Rhee

• Department of Psychological Sciences, University of London, London, United Kingdom

  Angelica Ronald

Soo Hyun Rhee, PhD is as associate professor in the Department of Psychology and Neuroscience and faculty fellow at the Institute for Behavioral Genetics at the University of Colorado-Boulder. She is currently working on a study examining a developmental model of conduct disorder in a longitudinal, genetically informative sample focusing on negative emotionality, daring, and lack of prosociality as early precursors of conduct problems. Angelina Ronald, PhD is a lecturer at the Centre for Brain and Cognitive Development in the Department of Psychological Sciences at Birkbeck, University of London. She is known for her behavior genetics research on developmental psychopathology. Dr. Ronald is a collaborator on several large twin studies and is also a scientific affiliate of the British Autism Study of Infant Siblings (BASIS).