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  • Book
  • © 2014

Focal Controlled Drug Delivery

Editors:

(view affiliations)
  • Includes fundamental introductory chapters for focal drug delivery

  • Describes drug delivery to body sites/system

  • Provides an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences

  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Delivery Science and Technology (ADST)

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USD 169.00
Price excludes VAT (USA)
  • ISBN: 978-1-4614-9434-8
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  • Readable on all devices
  • Own it forever
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  • Tax calculation will be finalised during checkout
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USD 219.99
Price excludes VAT (USA)
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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xvii
  2. Introductory Chapters

    1. Front Matter

      Pages 1-1
    2. Biodegradable Polymers for Focal Delivery Systems

      • Wahid Khan, Venu Gopala Swami Challa, Robert Langer, Abraham J. Domb
      Pages 3-32
    3. Implantable Medical Devices

      • Wahid Khan, Eameema Muntimadugu, Michael Jaffe, Abraham J. Domb
      Pages 33-59
    4. Systemic Targeting Systems-EPR Effect, Ligand Targeting Systems

      • Prasad V. Pawar, Abraham J. Domb, Neeraj Kumar
      Pages 61-91
    5. Polymer–Drug Conjugate in Focal Drug Delivery

      • Rajan Swami, Dinesh Kumar, Wahid Khan, Ramakrishna Sistla, Nalini Shastri
      Pages 117-147
  3. Delivery to Body Sites/Systems

    1. Front Matter

      Pages 167-167
    2. Treatment of Brain Tumors

      • Betty M. Tyler, Gustavo Pradilla, Uri Hadelsberg, Hansen Bow, Ian Suk, Henry Brem
      Pages 169-194
    3. Intranasal Delivery of Neuropeptide-Loaded Nanoparticles and Their Application to Nervous System Therapeutics

      • Michael J. Kubek, Abraham J. Domb, Daniel J. Kubek, Michael C. Veronesi
      Pages 195-213
    4. Nanotechnology-Based Ophthalmic Drug Delivery System

      • Fahima Dilnawaz, Sanjeeb Kumar Sahoo
      Pages 225-241
    5. Site-Specific Ocular Nucleic Acid Delivery

      • Ravi S. Shukla, Kun Cheng
      Pages 243-262
    6. Topical Iontophoresis for Targeted Local Drug Delivery to the Eye and Skin

      • Taís Gratieri, Yogeshvar N. Kalia
      Pages 263-284
    7. Local Drug Delivery to the Oral Cavity

      • Sheeba Qureshi, Wahid Khan, Michael Perez-Davidi, Ervin I Weiss, Nurit Beyth, Abraham J. Domb
      Pages 285-304
    8. Focal Drug Delivery for Management of Oral Infections

      • Nurit Beyth, Orith Haramaty, David Polak
      Pages 305-327
    9. Nanotechnology Applications in Local Arterial Drug Delivery

      • Dipti Deshpande, Aziza Jamal-Allial, Kinjal Sankhe, Mansoor Amiji
      Pages 359-385

About this book

The concept of Focal Drug Delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on this subject.  Thus, the aim of the proposed book “Focal Controlled Drug Delivery” is to bring together leading experts and researchers in this field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic.  This book contains two sections- first section includes fundamental introductory chapters for focal drug delivery whereas, second section includes chapters describing drug delivery to body sites/system. The book allows clinical, pharmaceutical and biological scientists to offer their own perspectives on the subject, making it of potential interest to a wider audience than just drug delivery scientists.

ABRAHAM J. DOMB is Professor for Medicinal Chemistry and Biopolymers at the Faculty of Medicine of the Hebrew University, Jerusalem, Israel. He earned Bachelor’s degrees in Chemistry, Pharmacy and Law studies and PhD degree in Chemistry from Hebrew University. He did his postdoctoral training at MIT and Harvard Univ. USA and was R&D manager at Nova Pharm. Co. Baltimore USA during 1988-1992. During 2007-2012 he headed the Division of Identification and Forensic Sciences of the Israel Police. His primary research interests are in biopolymers, controlled drug delivery, cancer therapy, nanoparticulate systems, and forensic sciences.

WAHID KHAN obtained his Master’s and PhD in Pharmaceutics at the National Institute of Pharmaceutical & Educational Research (NIPER) Mohali India and worked with Prof. Abraham J. Domb in The Hebrew University of Jerusalem, Israel for his post doctoral research. Currently, he is working as Assistant Professor in Department of Pharmaceutics, NIPER, Hyderabad, India. He is having experience of working in areas of drug delivery, drug targeting, nanomedicine and biodesign of implantable medical devices. Dr. Khan has also won various national and international awards and fellowships including- Israel government prestigious PBC fellowships for outstanding Post-doctoral Researcher, Valazzi-Pikovsky and Lady Davis fellowship award.

Keywords

  • biopolymers
  • focal controlled drug delivery
  • iontophoresis
  • liposomes
  • nanoparticles
  • targeted delivery

Editors and Affiliations

  • School of Pharmacy-Faculty of Medicine The Hebrew University of Jerusalem, Jerusalem, Israel

    Abraham J. Domb

  • Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Balanagar, Hyderabad, India

    Wahid Khan

About the editors

ABRAHAM J. DOMB is Professor for Medicinal Chemistry and Biopolymers at the Faculty of Medicine of the Hebrew University in Jerusalem, Israel.  He earned bachelor’s degrees in chemistry, pharmacy and law studies and a Ph.D. in chemistry from Hebrew University. He did his postdoctoral training at MIT and Harvard University and was R&D manager at Nova Pharm in Baltimore between 1988 and 1992. His primary research interests are in biopolymers, controlled drug delivery, cancer therapy, nanoparticulate systems, and forensic sciences.

 

WAHID KHAN obtained his master’s degree and Ph.D. in pharmaceutics at the National Institute of Pharmaceutical & Educational Research (NIPER) in Mohali, India. He worked with Prof. Abraham J. Domb in The Hebrew University of Jerusalem, Israel, for his post-doctoral research. Currently, he is working as Assistant Professor in the Department of Pharmaceutics at NIPER in Hyderabad, India. His experience includes areas ranging from drug delivery and drug targeting to nanomedicine and biodesign of implantable medical devices.

Bibliographic Information

  • Book Title: Focal Controlled Drug Delivery

  • Editors: Abraham J. Domb, Wahid Khan

  • Series Title: Advances in Delivery Science and Technology

  • DOI: https://doi.org/10.1007/978-1-4614-9434-8

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Controlled Release Society 2014

  • Hardcover ISBN: 978-1-4614-9433-1

  • Softcover ISBN: 978-1-4899-7965-0

  • eBook ISBN: 978-1-4614-9434-8

  • Series ISSN: 2192-6204

  • Series E-ISSN: 2192-6212

  • Edition Number: 1

  • Number of Pages: XVII, 700

  • Number of Illustrations: 25 b/w illustrations, 75 illustrations in colour

  • Topics: Pharmaceutics

Buying options

eBook
USD 169.00
Price excludes VAT (USA)
  • ISBN: 978-1-4614-9434-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 219.99
Price excludes VAT (USA)
Hardcover Book
USD 249.99
Price excludes VAT (USA)