© 2014

Intraoperative Imaging and Image-Guided Therapy

  • Ferenc A. Jolesz

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Ferenc A. Jolesz
    Pages 1-23
  3. The Fundamentals of Image Guidance

    1. Front Matter
      Pages 47-47
    2. Leo Joskowicz
      Pages 49-61
    3. Orçun Göksel, Gábor Székely
      Pages 63-77
    4. Tina Kapur, Jan Egger, Jagadeesan Jayender, Matthew Toews, William M. Wells
      Pages 79-91
    5. Kevin Cleary, Emmanuel Wilson, Sebastian Ordas, Filip Banovac
      Pages 93-105
    6. Jagadeesan Jayender, Kirby G. Vosburgh
      Pages 117-133
  4. Imaging Technologies and Methods for Image Guidance

    1. Front Matter
      Pages 135-135
    2. Prasheel V. Lillaney, Norbert J. Pelc, Rebecca Fahrig
      Pages 137-153
    3. Jeff Stoll
      Pages 155-162
    4. Pierre Khuri-Yakub, Ömer Oralkan, Amin Nikoozadeh
      Pages 163-171
    5. Rajiv Gupta, Conor Walsh, Irene S. Wang, Marc Kachelrieß, Jan Kuntz, Sönke Bartling
      Pages 173-191
    6. Lawrence P. Panych, Junichi Tokuda
      Pages 193-209
    7. Andriy Fedorov, Petter Risholm, William M. Wells
      Pages 211-223
    8. Marie Foley Kijewski, Clare M. C. Tempany, Alexandra J. Golby, Ferenc A. Jolesz
      Pages 225-232
    9. Niels J. Harlaar, Gooitzen M. van Dam, Vasilis Ntziachristos
      Pages 233-245
  5. Image-Guidance Technologies

    1. Front Matter
      Pages 247-247

About this book


Image-guided therapy (IGT) uses imaging to improve the localization and targeting of diseased tissue and to monitor and control treatments. During the past decade, image-guided surgeries and image-guided minimally invasive interventions have emerged as advances that can be used in place of traditional invasive approaches.  Advanced imaging technologies such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) entered into operating rooms and interventional suites to complement already-available routine imaging devices like X-ray and ultrasound.  At the same time, navigational tools, computer-assisted surgery devices, and image-guided robots also became part of the revolution in interventional radiology suites and the operating room. 


Intraoperative Imaging and Image-Guided Therapy explores the fundamental, technical, and clinical aspects of state-of the-art image-guided therapies.  It presents the basic concepts of image guidance, the technologies involved in therapy delivery, and the special requirements for the design and construction of image-guided operating rooms and interventional suites.  It also covers future developments such as molecular imaging-guided surgeries and novel innovative therapies like MRI-guided focused ultrasound surgery.


IGT is a multidisciplinary and multimodality field in which teams of physicians, nurses, and other professionals, such as physicists, engineers, and computer scientists, collaborate in performing these interventions, an approach that is reflected in the organization of the book.   Contributing authors include members of the  National Center of Image-Guided Therapy program at Brigham and Women’s Hospital and  international leaders in the field of IGT.


The book includes coverage of these topics:

- Imaging methods, guidance technologies, and the therapy delivery systems currently used or in development.

- Clinical applications for IGT in various specialties such as neurosurgery, ear-nose-and-throat surgery, cardiovascular surgery, endoscopic surgery, and orthopedic surgery.   

- Review and comparison of the clinical uses for IGT with conventional methods in terms of invasiveness, effectiveness, and outcome.

- Requirements for the design and construction of image-guided operating rooms and interventional suites.


Abdomen Bone Brain Breast Cardiovascular Image Guided Interventional Intra-operative Intraoperative MRI Neurosurgery Orthopedics Prostate Radiology Spine Surgery

Editors and affiliations

  • Ferenc A. Jolesz
    • 1
  1. 1.National Center for Image Guided Therapy, Department of RadiologyBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA

Bibliographic information


“This is an excellent book on all kinds of imaging techniques for brain, urologic, cardiac, and orthopedic surgery. … Engineers, physicists, students, and surgeons will find the full color pictures helpful. I highly reccommend this for surgical approaches employed in Minimally invasive surgeries, i.e. to be a guide for mapping and planning.” (Joseph J. Grenier,, September, 2015)

“This is a large book running to almost 900 pages. … the book provides a fascinating glimpse of how imaging may be used, both now and in the future, to increase the accuracy, efficacy and safety of therapeutic techniques. … it would be a valuable addition to any radiology library where the younger generation of radiologists, radiographers and physicists may find inspiration for future career decisions.” (Nick Reading, RAD Magazine, January, 2015)