Viral Entry into Host Cells

  • Stefan Pöhlmann
  • Graham Simmons

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 790)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Clare L. Jolly, Quentin J. Sattentau
    Pages 1-23
  3. Jeffrey M. Bergelson, Carolyn B. Coyne
    Pages 24-41
  4. Pranav Danthi, Geoffrey H. Holm, Thilo Stehle, Terence S. Dermody
    Pages 42-71
  5. Xiangjie Sun, Gary R. Whittaker
    Pages 72-82
  6. Graham Simmons
    Pages 83-94
  7. Katharine N. Bossart, Deborah L. Fusco, Christopher C. Broder
    Pages 95-127
  8. Dirk Lindemann, Imke Steffen, Stefan Pöhlmann
    Pages 128-149
  9. Yorgo Modis
    Pages 150-166
  10. Andrew D. Regan, Gary R. Whittaker
    Pages 167-177
  11. Claude Krummenacher, Andrea Carfí, Roselyn J. Eisenberg, Gary H. Cohen
    Pages 178-195
  12. Back Matter
    Pages 197-199

About this book

Introduction

For a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research.

Keywords

Apoptosis Host cell Reoviruses Viral entry

Editors and affiliations

  • Stefan Pöhlmann
    • 1
    • 2
  • Graham Simmons
    • 3
  1. 1.Institute for VirologyHannover Medical SchoolHannoverGermany
  2. 2.German Primate CenterGöttingenGermany
  3. 3.Blood Systems Research Institute, and Department of Laboratory MedicineUniversity of California San FranciscoSan FranciscoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4614-7651-1
  • Copyright Information Landes Bioscience and Springer Science+Business Media New York 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-7650-4
  • Online ISBN 978-1-4614-7651-1
  • Series Print ISSN 0065-2598
  • About this book