Editors:
Provides an overview of existing morphologic assessment strategies as well as developing novel technologies
Presents emerging “omics” techniques for recognizing potential gamete and embryo viability for implantation
Creates a unique resource for both practicing clinicians and researchers in the field of assisted reproduction
Gives expert knowledge of clinical practices and techniques, including their potential benefits and pitfalls
Includes supplementary material: sn.pub/extras
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Table of contents (26 chapters)
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Front Matter
About this book
In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates.
Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
Keywords
- ART
- Artificial insemination
- Assisted reproduction
- Genomics
- IVF
- In vitro fertilization
- Infertility
- Metabolomics
- Proteomics
Editors and Affiliations
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University of Melbourne, Department of Zoology, Melbourne, Australia
David K. Gardner
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Boston IVF, Waltham, USA
Denny Sakkas
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Yale School of Medicine, Dept. of Ob/Gyn & Reproductive Sciences, New Haven, USA
Emre Seli
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Obstetrics & Gynaecology, University of Oxford, Nuffield Department of, Oxford, United Kingdom
Dagan Wells
Bibliographic Information
Book Title: Human Gametes and Preimplantation Embryos
Book Subtitle: Assessment and Diagnosis
Editors: David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells
DOI: https://doi.org/10.1007/978-1-4614-6651-2
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-4614-6650-5Published: 27 May 2013
Softcover ISBN: 978-1-4939-4268-8Published: 23 August 2016
eBook ISBN: 978-1-4614-6651-2Published: 27 May 2013
Edition Number: 1
Number of Pages: XV, 306
Number of Illustrations: 16 b/w illustrations, 48 illustrations in colour
Topics: Reproductive Medicine, Midwifery, Gynecology