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  • © 2013

Human Gametes and Preimplantation Embryos

Assessment and Diagnosis

  • Provides an overview of existing morphologic assessment strategies as well as developing novel technologies

  • Presents emerging “omics” techniques for recognizing potential gamete and embryo viability for implantation

  • Creates a unique resource for both practicing clinicians and researchers in the field of assisted reproduction

  • Gives expert knowledge of clinical practices and techniques, including their potential benefits and pitfalls

  • Includes supplementary material: sn.pub/extras

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Softcover Book USD 119.99
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Hardcover Book USD 169.99
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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xv
  2. Analysis of the Zona Pellucida as an Indicator of Oocyte Developmental Potential

    • Markus Montag, Thomas Schimming, Maria Köster
    Pages 9-16
  3. Morphological Assessment of Oocytes, Pronuclear and Cleavage Stage Embryos

    • Laura Rienzi, Benedetta Iussig, Filippo Ubaldi
    Pages 17-30
  4. Real-Time Imaging Strategies to Improve Morphological Assessment

    • María Cruz, Manuel Muñoz, Marcos Meseguer
    Pages 45-53
  5. The Origins of Aneuploidy in Human Embryos

    • Elpida Fragouli, Joy Delhanty
    Pages 107-124
  6. Single Nucleotide Polymorphisms and Next Generation Sequencing

    • Alan H. Handyside, Dagan Wells
    Pages 135-145
  7. Mass Spectrometry, Proteomics, and the Study of Sperm Cell Biology

    • Mark A. Baker, R. John Aitken
    Pages 193-203
  8. Proteomic Analysis of Embryo Viability

    • Mandy G. Katz-Jaffe, Susanna McReynolds
    Pages 205-210

About this book

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates.

Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Editors and Affiliations

  • University of Melbourne, Department of Zoology, Melbourne, Australia

    David K. Gardner

  • Boston IVF, Waltham, USA

    Denny Sakkas

  • Yale School of Medicine, Dept. of Ob/Gyn & Reproductive Sciences, New Haven, USA

    Emre Seli

  • Obstetrics & Gynaecology, University of Oxford, Nuffield Department of, Oxford, United Kingdom

    Dagan Wells

Bibliographic Information

  • Book Title: Human Gametes and Preimplantation Embryos

  • Book Subtitle: Assessment and Diagnosis

  • Editors: David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells

  • DOI: https://doi.org/10.1007/978-1-4614-6651-2

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Hardcover ISBN: 978-1-4614-6650-5Published: 27 May 2013

  • Softcover ISBN: 978-1-4939-4268-8Published: 23 August 2016

  • eBook ISBN: 978-1-4614-6651-2Published: 27 May 2013

  • Edition Number: 1

  • Number of Pages: XV, 306

  • Number of Illustrations: 16 b/w illustrations, 48 illustrations in colour

  • Topics: Reproductive Medicine, Obstetrics/Perinatology/Midwifery, Gynecology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access