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  • Book
  • © 2013

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

  • Will address an important emergent area within immunomics: adjuvants

  • Explores ways to make vaccines more effective

  • There is no such book like this one

  • Includes supplementary material: sn.pub/extras

Part of the book series: Immunomics Reviews: (IMMUN, volume 5)

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eBook USD 139.00
Price excludes VAT (USA)
  • ISBN: 978-1-4614-5070-2
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 179.99
Price excludes VAT (USA)
Hardcover Book USD 219.99
Price excludes VAT (USA)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-x
  2. Bacterial Genomes and Vaccine Design

    • Valeria Cafardi, John L. Telford, Davide Serruto
    Pages 13-37
  3. Identification of Candidate Vaccine Antigens In Silico

    • Darren R. Flower, Matthew N. Davies, Irini A. Doytchinova
    Pages 39-71
  4. Post-genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T Cell Antigens of Mycobacterium bovis

    • Martin Vordermeier, Gareth J. Jones, Samantha Sampson, Stephen V. Gordon
    Pages 73-90
  5. On the Development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge

    • Hifzur Rahman Ansari, Darren R. Flower, Gajendra P. S. Raghava
    Pages 117-130
  6. Designing Liposomes as Vaccine Adjuvants

    • Malou Henriksen-Lacey, Yvonne Perrie
    Pages 181-203
  7. Designing Nonionic Surfactant Vesicles for the Delivery of Antigens for Systemic and Alternative Delivery Routes

    • Jitinder Wilkhu, Anil Vangala, Afzal R. Mohammed, Yvonne Perrie
    Pages 205-232
  8. Formulation and Characterisation of PLGA Microspheres as Vaccine Adjuvants

    • Daniel J. Kirby, Randip Kaur, Yvonne Perrie
    Pages 263-289
  9. Powder Vaccines for Pulmonary Delivery

    • Tom Jin, Eric Tsao
    Pages 291-301
  10. Back Matter

    Pages 305-314

About this book

Vaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jenner’s work in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world.

This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.

Keywords

  • Adjuvants
  • Antigens
  • Immunomics
  • Reverse Vaccinology
  • vaccines

Editors and Affiliations

  • Aston Pharmacy School, School of Life and Health Sciences, University of Aston, Birmingham, United Kingdom

    Darren R. Flower

  • Aston Pharmacy School, School of Life and Health Sciences, Aston University, Birmingham, United Kingdom

    Yvonne Perrie

About the editors

Dr. Darren R Flower. An interdisciplinary scientist, with special interest in bioinformatics, computational chemistry, and cheminformatics, Dr. Flower has wide-ranging experience of the pre-clinical research environment in both academia and the pharmaceutical industry. Before joining Aston University as a Reader, Dr. Flower was a Jenner Research Fellow and Principal Investigator at the University of Oxford; and formerly a Senior Group Leader managing a large research group at The Edward Jenner Institute for Vaccine Research. Before that, Dr. Flower was a drug discovery scientist in the Pharmaceutical industry. Dr. Flower is a Fellow of the Royal Society of Chemistry, and the author of over 150 research papers and reviews, and 7 Books, including the monograph: Bioinformatics for Vaccinology.

Professor Yvonne Perrie is Pharmacist whose research focuses on the development on delivery systems for drugs and vaccines. Prof. Perrie is currently Head of Pharmacy and Chair in Drug Delivery within Aston University.  Prof. Perrie received her Ph.D. from the University of London, UK where she investigated the use of liposomes for gene delivery under the supervision of Professor Gregory Gregoriadis. Prof. Perrie then joined a newly established Drug Delivery Company, Lipoxen Technologies Ltd., prior to taking her post at Aston University. Prof. Perrie is currently Chair of the UK and Ireland Controlled Release Society and has approximately 100 research papers and reviews focusing on the research and development of drug delivery systems.

Bibliographic Information

  • Book Title: Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

  • Editors: Darren R. Flower, Yvonne Perrie

  • Series Title: Immunomics Reviews:

  • DOI: https://doi.org/10.1007/978-1-4614-5070-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Hardcover ISBN: 978-1-4614-5069-6

  • Softcover ISBN: 978-1-4899-9795-1

  • eBook ISBN: 978-1-4614-5070-2

  • Series ISSN: 2628-5789

  • Series E-ISSN: 2628-5797

  • Edition Number: 1

  • Number of Pages: X, 314

  • Topics: Immunology, Bioinformatics, Pharmacology

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • ISBN: 978-1-4614-5070-2
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 179.99
Price excludes VAT (USA)
Hardcover Book USD 219.99
Price excludes VAT (USA)