RNA Interference from Biology to Therapeutics

Editors:

ISBN: 978-1-4614-4743-6 (Print) 978-1-4614-4744-3 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xv

  2. No Access

    Chapter

    Pages 1-29

    RNA Interference Pathways and Therapeutic Exploitation

  3. No Access

    Chapter

    Pages 31-56

    Synthetic Dicer-Substrate siRNAs as Triggers of RNA Interference

  4. No Access

    Chapter

    Pages 57-78

    The Role of MicroRNAs in Natural Tissue Development and Application in Regenerative Medicine

  5. No Access

    Chapter

    Pages 79-95

    Intracellular Delivery Considerations for RNAi Therapeutics

  6. No Access

    Chapter

    Pages 97-125

    Mucosal Delivery of RNAi Therapeutics

  7. No Access

    Chapter

    Pages 127-142

    Nanomedicines for Systemic Delivery of RNAi Therapeutics

  8. No Access

    Chapter

    Pages 143-160

    Lipidoids: A Combinatorial Approach to siRNA Delivery

  9. No Access

    Chapter

    Pages 161-184

    Polymeric Micelles for siRNA Delivery

  10. No Access

    Chapter

    Pages 185-205

    RNAi Therapeutic Delivery by Exosomes

  11. No Access

    Chapter

    Pages 207-220

    Aptamer-Mediated siRNA Targeting

  12. No Access

    Chapter

    Pages 221-242

    RNAi as Antiviral Therapy: The HIV-1 Case

  13. No Access

    Chapter

    Pages 243-257

    Genome-Wide RNAi Screening to Identify Human Host Factors Crucial for Influenza Virus Replication

  14. No Access

    Chapter

    Pages 259-298

    The Application of MicroRNAs in Cancer Diagnostics

  15. No Access

    Chapter

    Pages 299-314

    Therapeutic Application of MicroRNAs in Cancer

  16. No Access

    Chapter

    Pages 315-328

    Preclinical and Clinical Studies Employing RNA Interference as a Therapeutic for Respiratory Syncytial Virus (RSV) Infection in the Lung

  17. Back Matter

    Pages 329-337