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Ventricular/Vascular Coupling

Clinical, Physiological, and Engineering Aspects

  • Frank C. P. Yin

Table of contents

  1. Front Matter
    Pages i-xii
  2. Michael F. O’Rourke, Albert P. Avolio, Wilmer W. Nichols
    Pages 1-19
  3. Robert L. Engler, James W. Covell
    Pages 20-41
  4. Wilmer W. Nichols, Michael F. O’Rourke, Albert P. Avolio, Toshio Yaginuma, Joseph P. Murgo, Carl J. Pepine et al.
    Pages 79-114
  5. Frank C. P. Yin
    Pages 115-139
  6. Joseph P. Murgo, Nicolaas Westerhof
    Pages 140-158
  7. Gerardus J. van den Horn
    Pages 203-209
  8. Kenji Sunagawa, Kiichi Sagawa, W. Lowell Maughan
    Pages 210-239
  9. Joseph S. Janicki, Sanjeev G. Shroff, Karl T. Weber
    Pages 262-287
  10. Kenneth B. Campbell, John A. Ringo, N. S. Peterson
    Pages 288-300
  11. Terry W. Latson, Frank C. P. Yin, William C. Hunter
    Pages 334-383
  12. Frank C. P. Yin, Zhaorong Liu, Kenneth P. Brin
    Pages 384-398
  13. Back Matter
    Pages 399-406

About this book

Introduction

Physiologists have long been interested in the interaction, or coupling, between the heart and the vasculature. The early literature consists mainly of phenomenological descriptions of cardiac alterations resulting from specific interventions in the vasculature. Hundreds of studies, for example, describe functional aspects of hypertrophied myocardium associated with the excessive vascular loading produced by various types of experimental hypertension. Recently, the concepts of ventricular/vascular interaction have found important clinical application. The widespread use of vaso­ dilators and of intraaortic counterpUlsation balloons for unloading an ov­ erburdened, diseased heart is a prime example. Despite the interest in this field, until as recently as 20 years ago we were not able to describe ventricular or vascular function in a framework suitable for quantitatively expressing the interaction between these two complex systems. Three major developments-description of ventricular function in terms of both the time-varying elastance and the pump function graph and quantification of vascular function in terms of impedance­ have changed this. These functional descriptions now enable systems en­ gineers, bioengineers, physiologists, and clinicians to address very specific quantitative aspects of ventricular/vascular interaction and have resulted in a flurry of papers and symposia devoted to this subject.

Keywords

Bypass blood vessel hypertension pathophysiology physiology

Editors and affiliations

  • Frank C. P. Yin
    • 1
  1. 1.Department of MedicineJohns Hopkins Medical InstitutionsBaltimoreUSA

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