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Estrogens and Brain Function

Neural Analysis of a Hormone-Controlled Mammalian Reproductive Behavior

  • Donald W. Pfaff

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Donald W. Pfaff
      Pages 1-15
  3. Triggering the Behavior: Sensory and Ascending Pathways

    1. Front Matter
      Pages 17-17
    2. Donald W. Pfaff
      Pages 19-30
    3. Donald W. Pfaff
      Pages 31-43
    4. Donald W. Pfaff
      Pages 44-56
    5. Donald W. Pfaff
      Pages 57-74
  4. Facilitating the Behavior: Sex Hormones in the Brain

    1. Front Matter
      Pages 75-75
    2. Donald W. Pfaff
      Pages 106-127
    3. Donald W. Pfaff
      Pages 128-145
    4. Donald W. Pfaff
      Pages 146-168
  5. Executive Control over the Behavior: Descending and Motor Pathways

    1. Front Matter
      Pages 169-169
    2. Donald W. Pfaff
      Pages 171-194
    3. Donald W. Pfaff
      Pages 195-207
  6. Building on this Paradigm

    1. Front Matter
      Pages 209-209
    2. Donald W. Pfaff
      Pages 211-234
    3. Donald W. Pfaff
      Pages 235-239
    4. Donald W. Pfaff
      Pages 240-247
  7. Back Matter
    Pages 249-281

About this book

Introduction

This book brings together some of the results and ideas produced by a large number of people-colleagues and students with whom I am privileged to work in the laboratory at Rockefeller University. In terms of my personal history I see it as a confluence of creative forces­ persons from whom I have learned. I was instructed in neuroanatomy by Walle J. H. Nauta at M. I. T. , and later in a course at Harvard Medical School under the direction of Richard Sidman. At Harvard Medical School, where M. I. T. graduate students were allowed to cross register, the superb neurophysiology course was under the guiding spirit of Stephen Kuffler. Later, I benefited greatly from participating in his summer course in electrophysiological techniques at Woods Hole. Eric Kandel and his colleagues have provided us with the most exciting contemporary approach to the conceptualization and study of cellular mechanisms for behavior. Here at Rockefeller, Carl Pfaffmann and Neal Miller have been leaders in every sense of the word. Not only did they provide me with opportunities to grow to scientific maturity; they also set an example of clear thinking about mechanisms for mammalian behavior patterns. I wrote this book to show how the systematic use of increasingly detailed electrophysiological, neuroanatomical, and neuroendocrine tech­ niques can explain the mechanism for a mammalian behavioral response. The behavior in question happens to be sensitive to steroid hormones and plays a central role in reproduction.

Keywords

Brain Function Gehirn Hormonale Regulation Nervous System Pfaff Sexualhormon Sexualität Säugetiere brainstem estrogen action neural mechanisms neurons physiology

Authors and affiliations

  • Donald W. Pfaff
    • 1
  1. 1.The Rockefeller UniversityNew YorkUSA

Bibliographic information